Woman reading in MDC library

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in Aging Cell

The conserved histone chaperone LIN-53 is required for normal lifespan and maintenance of muscle integrity in Caenorhabditis elegans.

S. Müthel et al.
in JCI Insight

Transcriptional heterogeneity of fibroblasts is a hallmark of the aging heart

R. Vidal et al.
in Eur Heart J

Protease-activated receptor 2 deficiency mediates cardiac fibrosis and diastolic dysfunction

J. Friebel et al.
in Cell Rep

53BP1 supports immunoglobulin class switch recombination independently of its DNA double-strand break end protection function

D. Sundaravinayagam et al.
in Sci Rep

The cell adhesion protein CAR is a negative regulator of synaptic transmission

U. Wrackmeyer et al.
in Circulation

Deleting full length titin versus the titin M-band region leads to differential mechanosignaling and cardiac phenotypes

M.H. Radke et al.
in Leukemia

The AP-1-BATF and -BATF3 module is essential for growth, survival and TH17/ILC3 skewing of anaplastic large cell lymphoma

N. Schleussner et al.
in Cell Rep

Transient N-6-methyladenosine transcriptome sequencing reveals a regulatory role of m6A in splicing efficiency

A. Louloupi et al.
in PLoS ONE

Drug discovery with an RBM20 dependent titin splice reporter identifies cardenolides as lead structures to improve cardiac filling

M. Liss et al.
in J Neurosci

Graded elevation of c-Jun in Schwann cells in vivo: gene dosage determines effects on development, remyelination, tumorigenesis, and hypomyelination

S.V. Fazal et al.