Veröffentlichungen | MDC Berlin

11 Ergebnisse:

Active Filter:

10. Dezember 2020 in J Med Chem

From pyrazolones to azaindoles: evolution of active-site SHP2 inhibitors based on scaffold hopping and bioisosteric replacement

Y. Mostinski
G.J.J.E. Heynen
M.P. López-Alberca
J. Paul
S. Miksche
S. Radetzki
D. Schaller
E. Shanina
C. Seyffarth
Y. Kolomeets
N. Ziebart
J. de Schryver
S. Oestreich
M. Neuenschwander
Y. Roske
U. Heinemann
C. Rademacher
A. Volkamer
J.P. von Kries
W. Birchmeier
M. Nazaré

24. November 2020 in Proc Natl Acad Sci U S A

Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells

M. Barone
M. Müller
S. Chiha
J. Ren
D. Albat
A. Soicke
S. Dohmen
M. Klein
J. Bruns
M. van Dinther
R. Opitz
P. Lindemann
M. Beerbaum
K. Motzny
Y. Roske
P. Schmieder
R. Volkmer
M. Nazaré
U. Heinemann
H. Oschkinat
P. Ten Dijke
H.G. Schmalz
R. Kühne

01. August 2020 in J Struct Biol

Crystal structure of Q4D6Q6, a conserved kinetoplastid-specific protein from Trypanosoma cruzi

E. Dias D'Andréa
Y. Roske
G.A.P. de Oliveira
N. Cremer
A. Diehl
P. Schmieder
U. Heinemann
H. Oschkinat
J. Ricardo Pires

05. Mai 2020 in Symmetry

Symmetry in nucleic-acid double helices

U. Heinemann
Y. Roske

05. März 2020 in Biochem Biophys Res Commun

Structure of the active GGEEF domain of a diguanylate cyclase from Vibrio cholerae

O.P. Chouhan
Y. Roske
U. Heinemann
S. Biswas

21. Dezember 2010 in Proc Natl Acad Sci U S A

Bidirectional binding of invariant chain peptides to an MHC class II molecule

S. Guenther
A. Schlundt
J. Sticht
Y. Roske
U. Heinemann
K.H. Wiesmueller
G. Jung
K. Falk
O. Roetzschke
C. Freund

01. August 2010 in Cell Mol Life Sci

Characterization of the self-palmitoylation activity of the transport protein particle component Bet3

D. Kuemmel
J. Walter
M. Heck
U. Heinemann
M. Veit

01. Mai 2010 in Mol Cell Biol

Repression of transcriptional activity of C/EBPα by E2F-DP complexes

K. Zaragoza
V. Bégay
A. Schuetz
U. Heinemann
A. Leutz

01. März 2010 in FEBS J

Crystal structure of Klebsiella sp. ASR1 phytase suggests substrate binding to a preformed active site that meets the requirements of a plant rhizosphere enzyme

K. Boehm
T. Herter
J.J. Mueller
R. Borriss
U. Heinemann

24. Februar 2010 in J Neurosci

The coxsackievirus-adenovirus receptor reveals complex homophilic and heterophilic interactions on neural cells

C. Patzke
K.E. Max
J. Behlke
J. Schreiber
H. Schmidt
A.A. Dorner
S. Kroeger
M. Henning
A. Otto
U. Heinemann
F.G. Rathjen