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01. Mai 2012 in Nat Med

RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing

W. Guo
S. Schafer
M.L. Greaser
M.H. Radke
M. Liss
T. Govindarajan
H. Maatz
H. Schulz
S.E. Lincoln
A.M. Parrish
V. Dauksaite
P. Vakeel
S. Klaassen
B. Gerull
L. Thierfelder
V. Regitz-Zagrosek
T.A. Hacker
K.W. Saupe
G.W. Dec
P.T. Ellinor
C.A. MacRae
B. Spallek
R. Fischer
A. Perrot
C. Ozcelik
K. Saar
N. Hubner
M. Gotthardt

16. Oktober 2009 in J Mol Biol

Altered contractility of skeletal muscle in mice deficient in titin's M-band region

C.A. Ottenheijm
C. Hidalgo
K. Rost
M. Gotthardt
H. Granzier

11. September 2009 in Circ Res

Truncation of titin's elastic PEVK region leads to cardiomyopathy with diastolic dysfunction

H.L. Granzier
M.H. Radke
J. Peng
D. Westermann
O.L. Nelson
K. Rost
N.M. King
Q. Yu
C. Tschoepe
M. McNabb
D.F. Larson
S. Labeit
M. Gotthardt

01. September 2009 in Basic Res Cardiol

Enhancement of the endothelial NO synthase attenuates experimental diastolic heart failure

D. Westermann
A. Riad
U. Richter
S. Jaeger
K. Savvatis
M. Schuchardt
N. Bergmann
M. Toelle
D. Nagorsen
M. Gotthardt
H.P. Schultheiss
C. Tschoepe

01. September 2009 in J Mol Med

CAR-diology - a virus receptor in the healthy and diseased heart

R. Fischer
W. Poller
H.P. Schultheiss
M. Gotthardt

07. April 2009 in J Am Coll Cardiol

Cardiac deletion of the coxsackievirus-adenovirus receptor abolishes coxsackievirus b3 infection and prevents myocarditis in vivo

Y. Shi
C. Chen
U. Lisewski
U. Wrackmeyer
M. Radke
D. Westermann
M. Sauter
C. Tschoepe
W. Poller
K. Klingel
M. Gotthardt

01. November 2007 in Nat Neurosci

Roles for the pro-neurotrophin receptor sortilin in neuronal development, aging and brain injury

P. Jansen
K. Giehl
J.R. Nyengaard
K. Teng
O. Lioubinski
S.S. Sjoegaard
T. Breiderhoff
M. Gotthardt
F. Lin
A. Eilers
C.M. Petersen
G.R. Lewin
B.L. Hempstead
T.E. Willnow
A. Nykjaer

01. August 2007 in Am J Physiol Regul Integr Comp Physiol

Functional genomics of chicken, mouse, and human titin supports splice diversity as an important mechanism for regulating biomechanics of striated muscle

H. Granzier
M. Radke
J. Royal
Y. Wu
T.C. Irving
M. Gotthardt
S. Labeit

27. Februar 2007 in Proc Natl Acad Sci U S A

Targeted deletion of titin N2B region leads to diastolic dysfunction and cardiac atrophy

M.H. Radke
J. Peng
Y. Wu
M. McNabb
O.L. Nelson
H. Granzier
M. Gotthardt

13. Februar 2007 in Circulation

Cardiac hypertrophy and reduced contractility in hearts deficient in the titin kinase region

J. Peng
K. Raddatz
J.D. Molkentin
Y. Wu
S. Labeit
H. Granzier
M. Gotthardt