Veröffentlichungen | Max Delbrück Center

13 Ergebnisse:

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02. November 2020 / Sci Rep

Assessment of nanoindentation in stiffness measurement of soft biomaterials: kidney, liver, spleen and uterus

G. Wu
M. Gotthardt
M. Gollasch

08. September 2020 / Cell Rep

iPSC modeling of RBM20-deficient DCM identifies upregulation of RBM20 as a therapeutic strategy

F. Briganti
H. Sun
W. Wei
J. Wu
C. Zhu
M. Liss
I. Karakikes
S. Rego
A. Cipriano
M. Snyder
B. Meder
Z. Xu
G. Millat
M. Gotthardt
M. Mercola
L.M. Steinmetz

19. Juni 2020 / Nat Commun

Deconstructing sarcomeric structure-function relations in titin-BioID knock-in mice

F. Rudolph
C. Fink
J. Hüttemeister
M. Kirchner
M.H. Radke
J. Lopez Carballo
E. Wagner
T. Kohl
S.E. Lehnart
P. Mertins
M. Gotthardt

29. Mai 2020 / Front Physiol

Deleting titin's C-terminal PEVK exons increases passive stiffness, alters splicing, and induces cross-sectional and longitudinal hypertrophy in skeletal muscle

R.J. van der Pijl
B. Hudson
T. Granzier-Nakajima
F. Li
A.M. Knottnerus
J. Smith
C.S. Chung
M. Gotthardt
H.L. Granzier
C.A.C. Ottenheijm

01. Januar 2020 / Am J Physiol Cell Physiol

Real-time visualization of titin dynamics reveals extensive reversible photobleaching in human induced pluripotent stem cell-derived cardiomyocytes

A.G. Cadar
T.K. Feaster
K.R. Bersell
L. Wang
T.T. Hong
J.A. Balsamo
Z. Zhang
Y.W. Chun
Y.J. Nam
M. Gotthardt
B.C. Knollmann
D.M. Roden
C.C. Lim
C.C. Hong

01. Juli 2013 / Arch Biochem Biophys

Calcium sensitivity and myofilament lattice structure in titin N2B KO mice

E.J. Lee
J. Nedrud
P. Schemmel
M. Gotthardt
T.C. Irving
H.L. Granzier

01. Februar 2013 / Hypertension

Loss of epidermal growth factor receptor in vascular smooth muscle cells and cardiomyocytes causes arterial hypotension and cardiac hypertrophy

B. Schreier
S. Rabe
B. Schneider
M. Bretschneider
S. Rupp
S. Ruhs
J. Neumann
U. Rueckschloss
M. Sibilia
M. Gotthardt
C. Grossmann
M. Gekle

16. Oktober 2009 / J Mol Biol

Altered contractility of skeletal muscle in mice deficient in titin's M-band region

C.A. Ottenheijm
C. Hidalgo
K. Rost
M. Gotthardt
H. Granzier

11. September 2009 / Circ Res

Truncation of titin's elastic PEVK region leads to cardiomyopathy with diastolic dysfunction

H.L. Granzier
M.H. Radke
J. Peng
D. Westermann
O.L. Nelson
K. Rost
N.M. King
Q. Yu
C. Tschoepe
M. McNabb
D.F. Larson
S. Labeit
M. Gotthardt

01. September 2009 / Basic Res Cardiol

Enhancement of the endothelial NO synthase attenuates experimental diastolic heart failure

D. Westermann
A. Riad
U. Richter
S. Jaeger
K. Savvatis
M. Schuchardt
N. Bergmann
M. Toelle
D. Nagorsen
M. Gotthardt
H.P. Schultheiss
C. Tschoepe