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in Mol Ther

CAR T cells with enhanced sensitivity to B cell maturation antigen for the targeting of B cell non-Hodgkin's lymphoma and multiple myeloma

  • J. Bluhm
  • E. Kieback
  • S.F. Marino
  • F. Oden
  • J. Westermann
  • M. Chmielewski
  • H. Abken
  • W. Uckert
  • U.E. Höpken
  • A. Rehm
in Hum Gene Ther

Efficient non-viral T cell engineering by Sleeping Beauty minicircles diminishing DNA toxicity and miRNAs silencing the endogenous TCR

  • J. Clauss
  • M. Obenaus
  • C. Miskey
  • Z. Ivics
  • Z. Izsvák
  • W. Uckert
  • M. Bunse
in Nature

Tumour ischaemia by interferon-γ resembles physiological blood vessel regression

  • T. Kammertoens
  • C. Friese
  • A. Arina
  • C. Idel
  • D. Briesemeister
  • M. Rothe
  • A. Ivanov
  • A. Szymborska
  • G. Patone
  • S. Kunz
  • D. Sommermeyer
  • B. Engels
  • M. Leisegang
  • A. Textor
  • H.J. Fehling
  • M. Fruttiger
  • M. Lohoff
  • A. Herrmann
  • H. Yu
  • R. Weichselbaum
  • W. Uckert
  • N. Hübner
  • H. Gerhardt
  • D. Beule
  • H. Schreiber
  • T. Blankenstein
in Immunity

Thymus-derived regulatory T cells are positively selected on natural self-antigen through cognate interactions of high functional avidity

  • E. Kieback
  • E. Hilgenberg
  • U. Stervbo
  • V. Lampropoulou
  • P. Shen
  • M. Bunse
  • Y. Jaimes
  • P. Boudinot
  • A. Radbruch
  • U. Klemm
  • A.A. Kühl
  • R. Liblau
  • N. Hoevelmeyer
  • S.M. Anderton
  • W. Uckert
  • S. Fillatreau
in J Clin Invest

Targeting human melanoma neoantigens by T cell receptor gene therapy

  • M. Leisegang
  • T. Kammertoens
  • W. Uckert
  • T. Blankenstein
in Curr Opin Immunol

Targeting cancer-specific mutations by T cell receptor gene therapy

  • T. Blankenstein
  • M. Leisegang
  • W. Uckert
  • H. Schreiber
in Nat Biotechnol

Identification of human T-cell receptors with optimal affinity to cancer antigens using antigen-negative humanized mice

  • M. Obenaus
  • C. Leitão
  • M. Leisegang
  • X. Chen
  • I. Gavvovidis
  • P. van der Bruggen
  • W. Uckert
  • D.J. Schendel
  • T. Blankenstein
in Eur J Immunol

Misinitiation of intrathymic MART-1 transcription and biased TCR usage explain the high frequency of MART-1-specific T cells

  • S. Pinto
  • D. Sommermeyer
  • C. Michel
  • S. Wilde
  • D. Schendel
  • W. Uckert
  • T. Blankenstein
  • B. Kyewski
in Blood

The only proposed T-cell epitope derived from the TEL-AML1 translocation is not naturally processed

  • J. Popovic
  • L.P. Li
  • P.M. Kloetzel
  • M. Leisegang
  • W. Uckert
  • T. Blankenstein
in Int J Cancer

Tumor rejection by local interferon gamma induction in established tumors is associated with blood vessel destruction and necrosis

  • D. Briesemeister
  • D. Sommermeyer
  • C. Loddenkemper
  • R. Loew
  • W. Uckert
  • T. Blankenstein
  • T. Kammertoens