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in J Med Chem

Structure-based design of xanthine-benzimidazole derivatives as novel and potent tryptophan hydroxylase inhibitors

  • E. Specker
  • S. Matthes
  • R. Wesolowski
  • A. Schütz
  • M. Grohmann
  • N. Alenina
  • D. Pleimes
  • K. Mallow
  • M. Neuenschwander
  • A. Gogolin
  • M. Weise
  • J. Pfeifer
  • N. Ziebart
  • U. Heinemann
  • J.P. von Kries
  • M. Nazaré
  • M. Bader
in Blood Adv

SUMOylation inhibition overcomes proteasome inhibitor resistance in multiple myeloma

  • G.J.J.E. Heynen
  • F. Baumgartner
  • M. Heider
  • U. Patra
  • M. Holz
  • J. Braune
  • M. Kaiser
  • I. Schäffer
  • S.A. Bamopoulos
  • E. Ramberger
  • A. Murgai
  • Y.L.D. Ng
  • U.M. Demel
  • D. Laue
  • S. Liebig
  • J. Krüger
  • M. Janz
  • A. Nogai
  • M. Schick
  • P. Mertins
  • S. Müller
  • F. Bassermann
  • J. Krönke
  • U. Keller
  • M. Wirth
in Nat Commun

Therapeutic targeting of ATR in alveolar rhabdomyosarcoma

  • H. Dorado Garcia
  • F. Pusch
  • Y. Bei
  • J. von Stebut
  • G. Ibáñez
  • K. Guillan
  • K. Imami
  • D. Gürgen
  • J. Rolff
  • K. Helmsauer
  • S. Meyer-Liesener
  • N. Timme
  • V. Bardinet
  • R. Chamorro González
  • I.C. MacArthur
  • C.Y. Chen
  • J. Schulz
  • A.M. Wengner
  • C. Furth
  • B. Lala
  • A. Eggert
  • G. Seifert
  • P. Hundsoerfer
  • M. Kirchner
  • P. Mertins
  • M. Selbach
  • A. Lissat
  • F. Dubois
  • D. Horst
  • J.H. Schulte
  • S. Spuler
  • D. You
  • F. Dela Cruz
  • A.L. Kung
  • K. Haase
  • M. Di Virgilio
  • M. Scheer
  • M.V. Ortiz
  • A.G. Henssen
in Cancers

Core-clock genes regulate proliferation and invasion via a reciprocal interplay with MACC1 in colorectal cancer cells

  • A. Basti
  • D. Malhan
  • M. Dumbani
  • M. Dahlmann
  • U. Stein
  • A. Relógio
in Metab Eng

Metabolic reprogramming of synovial fibroblasts in osteoarthritis by inhibition of pathologically overexpressed pyruvate dehydrogenase kinases

  • A. Damerau
  • M. Kirchner
  • M. Pfeiffenberger
  • L. Ehlers
  • D.H. Do Nguyen
  • P. Mertins
  • B. Bartek
  • T. Maleitzke
  • Y. Palmowski
  • S. Hardt
  • T. Winkler
  • F. Buttgereit
  • T. Gaber
in Cancers

MACC1-induced collective migration is promoted by proliferation rather than single cell biomechanics

  • T. Hohmann
  • U. Hohmann
  • M. Dahlmann
  • D. Kobelt
  • U. Stein
  • F. Dehghani
in Allergy

The SCF/KIT axis in human mast cells: capicua acts as potent KIT repressor and ERK predominates PI3K

  • K. Franke
  • M. Kirchner
  • P. Mertins
  • T. Zuberbier
  • M. Babina
in Biotechniques

SUMOylation of the chromodomain factor MRG-1 in C. elegans affects chromatin-regulatory dynamics

  • G. Baytek
  • A. Blume
  • F.G. Demirel
  • S. Bulut
  • O. Popp
  • P. Mertins
  • B. Tursun
in Br J Cancer

Calcium-binding protein S100P is a new target gene of MACC1, drives colorectal cancer metastasis and serves as a prognostic biomarker

  • F. Schmid
  • M. Dahlmann
  • H. Röhrich
  • D. Kobelt
  • J. Hoffmann
  • S. Burock
  • W. Walther
  • U. Stein
in Int J Mol Sci

The anti-glucocorticoid receptor antibody clone 5E4: raising awareness of unspecific antibody binding

  • L. Ehlers
  • M. Kirchner
  • P. Mertins
  • C. Strehl
  • F. Buttgereit
  • T. Gaber