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in Sci Rep

Proteomic and transcriptomic changes in hibernating grizzly bears reveal metabolic and signaling pathways that protect against muscle atrophy

  • D.A. Mugahid
  • T.G. Sengul
  • X. You
  • Y. Wang
  • L. Steil
  • N. Bergmann
  • M.H. Radke
  • A. Ofenbauer
  • M. Gesell-Salazar
  • A. Balogh
  • S. Kempa
  • B. Tursun
  • C.T. Robbins
  • U. Völker
  • W. Chen
  • L. Nelson
  • M. Gotthardt
in Hum Mol Genet

Microtubule cytoskeleton regulates connexin 43 localization and cardiac conduction in cardiomyopathy caused by mutation in A-type lamins gene

  • C. Macquart
  • R. Jüttner
  • C. Le Dour
  • M. Chatzifrangkeskou
  • A. Schmitt
  • M. Gotthardt
  • G. Bonne
  • A. Muchir
in Proc Natl Acad Sci U S A

Resolving titin's lifecycle and the spatial organization of protein turnover in mouse cardiomyocytes

  • F. Rudolph
  • J. Hüttemeister
  • K. da Silva Lopes
  • R. Jüttner
  • L. Yu
  • N. Bergmann
  • D. Friedrich
  • S. Preibisch
  • E. Wagner
  • S.E. Lehnart
  • C.C. Gregorio
  • M. Gotthardt
in Eur Heart J

Protease-activated receptor 2 deficiency mediates cardiac fibrosis and diastolic dysfunction

  • J. Friebel
  • A. Weithauser
  • M. Witkowski
  • B.H. Rauch
  • K. Savvatis
  • A. Dörner
  • T. Tabaraie
  • M. Kasner
  • V. Moos
  • D. Bösel
  • M. Gotthardt
  • M.H. Radke
  • M. Wegner
  • P. Bobbert
  • D. Lassner
  • C. Tschöpe
  • H.P. Schutheiss
  • S.B. Felix
  • U. Landmesser
  • U. Rauch
in Sci Rep

The cell adhesion protein CAR is a negative regulator of synaptic transmission

  • U. Wrackmeyer
  • J. Kaldrack
  • R. Jüttner
  • U. Pannasch
  • N. Gimber
  • F. Freiberg
  • B. Purfürst
  • D. Kainmueller
  • D. Schmitz
  • V. Haucke
  • F.G. Rathjen
  • M. Gotthardt
in Circulation

Deleting full length titin versus the titin M-band region leads to differential mechanosignaling and cardiac phenotypes

  • M.H. Radke
  • C. Polack
  • M. Methawasin
  • C. Fink
  • H.L. Granzier
  • M. Gotthardt
in J Allergy Clin Immunol

Eleven loci with new reproducible genetic associations with allergic disease risk

  • M.A. Ferreira
  • J.M. Vonk
  • H. Baurecht
  • I. Marenholz
  • C. Tian
  • J.D. Hoffman
  • Q. Helmer
  • A. Tillander
  • V. Ullemar
  • Y. Lu
  • F. Rüschendorf
  • D.A. Hinds
  • N. Hübner
  • S. Weidinger
  • P.K. Magnusson
  • E. Jorgenson
  • Y.A. Lee
  • D.I. Boomsma
  • R. Karlsson
  • C. Almqvist
  • G.H. Koppelman
  • L. Paternoster
in J Gen Physiol

Metformin improves diastolic function in an HFpEF-like mouse model by increasing titin compliance

  • R.E. Slater
  • J.G. Strom
  • Mei Methawasin
  • M. Liss
  • M. Gotthardt
  • N. Sweitzer
  • H.L. Granzier
in Nat Med

RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing

  • W. Guo
  • S. Schafer
  • M.L. Greaser
  • M.H. Radke
  • M. Liss
  • T. Govindarajan
  • H. Maatz
  • H. Schulz
  • S.E. Lincoln
  • A.M. Parrish
  • V. Dauksaite
  • P. Vakeel
  • S. Klaassen
  • B. Gerull
  • L. Thierfelder
  • V. Regitz-Zagrosek
  • T.A. Hacker
  • K.W. Saupe
  • G.W. Dec
  • P.T. Ellinor
  • C.A. MacRae
  • B. Spallek
  • R. Fischer
  • A. Perrot
  • C. Ozcelik
  • K. Saar
  • N. Hubner
  • M. Gotthardt
in BMC Med Genet

Multi-locus stepwise regression: a haplotype-based algorithm for finding genetic associations applied to atopic dermatitis

  • S. Knuppel
  • J. Esparza-Gordillo
  • I. Marenholz
  • H. Holzhutter
  • A. Bauerfeind
  • A. Ruether
  • S. Weidinger
  • Y.A. Lee
  • K. Rohde