Wissenschaftliche Publikationen

Consequences of epidermal growth factor receptor (ErbB1) loss for vascular smooth muscle cells from mice with targeted deletion of ErbB1

B. Schreier
M. Doehler
S. Rabe
B. Schneider
G. Schwerdt
S. Ruhs
M. Sibilia
M. Gotthardt
M. Gekle
C. Grossmann

Physiology of microglia

H. Kettenmann
U.K. Hanisch
M. Noda
A. Verkhratsky

Transmitter- and hormone-activated Ca(2+) responses in adult microglia/brain macrophages in situ recorded after viral transduction of a recombinant Ca(2+) sensor

S. Seifert
M. Pannell
W. Uckert
K. Faerber
H. Kettenmann

12. Mai 2011 / J Med Chem

Elucidation of a structural basis for the inhibitor-driven, p62 (SQSTM1)-dependent intracellular redistribution of cAMP phosphodiesterase-4A4 (PDE4A4)

J.P. Day
B. Lindsay
T. Riddell
Z. Jiang
R.W. Allcock
A. Abraham
S. Sookup
F. Christian
J. Bogum
E.K. Martin
R.L. Rae
D. Anthony
G.M. Rosair
D.M. Houslay
E. Huston
G.S. Baillie
E. Klussmann
M.D. Houslay
D.R. Adams

Routes of epithelial water flow: aquaporins versus cotransporters

R. Mollajew
F. Zocher
A. Horner
B. Wiesner
E. Klussmann
P. Pohl

Selective SUMO modification of cAMP-specific phosphodiesterase-4D5 (PDE4D5) regulates the functional consequences of phosphorylation by PKA and ERK

X. Li
S. Vadrevu
A. Dunlop
J. Day
N. Advant
J. Troeger
E. Klussmann
E. Jaffrey
R.T. Hay
D.R. Adams
M.D. Houslay
G.S. Baillie

MEK1 binds directly to βarrestin1, influencing both its phosphorylation by ERK and the timing of its isoprenaline-stimulated internalization

D. Meng
M.J. Lynch
E. Huston
M. Beyermann
J. Eichhorst
D.R. Adams
E. Klussmann
M.D. Houslay
G.S. Baillie

1H NMR structural and functional characterisation of a cAMP-specific phosphodiesterase-4D5 (PDE4D5) N-terminal region peptide that disrupts PDE4D5 interaction with the signalling scaffold proteins, beta-arrestin and RACK1

K.J. Smith
G.S. Baillie
E.I. Hyde
X. Li
T.M. Houslay
A. McCahill
A.J. Dunlop
G.B. Bolger
E. Klussmann
D.R. Adams
M.D. Houslay

Isoform-selective susceptibility of DISC1/phosphodiesterase-4 complexes to dissociation by elevated intracellular cAMP levels

H. Murdoch
S. Mackie
D.M. Collins
E.V. Hill
G.B. Bolger
E. Klussmann
D.J. Porteous
J.K. Millar
M.D. Houslay

p75 neurotrophin receptor regulates tissue fibrosis through inhibition of plasminogen activation via a PDE4/cAMP/PKA pathway

B.D. Sachs
G.S. Baillie
J.R. McCall
M.A. Passino
C. Schachtrup
D.A. Wallace
A.J. Dunlop
K.F. MacKenzie
E. Klussmann
M.J. Lynch
S.L. Sikorski
T. Nuriel
I. Tsigelny
J. Zhang
M.D. Houslay
M.V. Chao
K. Akassoglou