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in Canc Res

Chimeric PD-1:28 receptor upgrades low-avidity T cells and restores effector function of tumor-infiltrating lymphocytes for adoptive cell therapy

R. Schlenker et al.
in Nature

Tumour ischaemia by interferon-γ resembles physiological blood vessel regression

T. Kammertoens et al.
in Clin Cancer Res

Eradication of large solid tumors by gene therapy with a T cell receptor targeting a single cancer-specific point mutation

M. Leisegang et al.
in J Clin Invest

Targeting human melanoma neoantigens by T cell receptor gene therapy

M. Leisegang et al.
in BIOspektrum

Designer T cells - New possibilities for immunotherapy of cancer [Designer-T-Zellen - neue Möglichkeiten für die Immuntherapie von Krebs]

M. Leisegang et al.
in Curr Opin Immunol

Targeting cancer-specific mutations by T cell receptor gene therapy

T. Blankenstein et al.
in Nat Biotechnol

Identification of human T-cell receptors with optimal affinity to cancer antigens using antigen-negative humanized mice

M. Obenaus et al.
in Hum Gene Ther Clin Dev

HEK293-based production platform for γ-retroviral (SIN-) vectors: application for safe and efficient transfer of COL7A1 cDNA

K. Hennig et al.
in J Virol

Protective capacity of virus-specific T cell receptor (TCR)-transduced CD8 T cells in vivo

K. Mueller et al.
in J Immunol

Human antitumor CD8+ T cells producing Th1 polycytokines show superior antigen sensitivity and tumor recognition

S. Wilde et al.