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28. März 2019 in Blood

Autocrine LTA signaling drives NF-κB and JAK-STAT activity and myeloid gene expression in Hodgkin lymphoma

L. von Hoff
E. Kärgel
V. Franke
E. McShane
K.W. Schulz-Beiss
G. Patone
N. Schleussner
M. Kolesnichenko
N. Hübner
O. Daumke
M. Selbach
A. Akalin
S. Mathas
C. Scheidereit

03. Mai 2016 in Proc Natl Acad Sci U S A

Canonical NF-κB signaling is uniquely required for the long-term persistence of functional mature B cells

E. Derudder
S. Herzog
V. Labi
T. Yasuda
K. Köchert
M. Janz
A. Villunger
M. Schmidt-Supprian
K. Rajewsky

17. März 2016 in Genome Med

A roadmap of constitutive NF-κB activity in Hodgkin lymphoma: dominant roles of p50 and p52 revealed by genome-wide analyses

K.A.P. de Oliveira
E. Kaergel
M. Heinig
J.F. Fontaine
G. Patone
E.M. Muro
S. Mathas
M. Hummel
M.A. Andrade-Navarro
N. Hübner
C. Scheidereit

01. Januar 2015 in Blood

Essential role of IRF4 and MYC signaling for survival of anaplastic large cell lymphoma

A. Weilemann
M. Grau
T. Erdmann
O. Merkel
U. Sobhiafshar
I. Anagnostopoulos
M. Hummel
A. Siegert
C. Hayford
H. Madle
B. Wollert-Wulf
I. Fichtner
B. Dörken
S. Dirnhofer
S. Mathas
M. Janz
N.C.T. Emre
A. Rosenwald
G. Ott
P. Lenz
A. Tzankov
G. Lenz

21. Oktober 2014 in Proc Natl Acad Sci U S A

Mapping of transcription factor motifs in active chromatin identifies IRF5 as key regulator in classical Hodgkin lymphoma

S. Kreher
M.A. Bouhlel
P. Cauchy
B. Lamprecht
S. Li
M. Grau
F. Hummel
K. Köchert
I. Anagnostopoulos
K. Jöhrens
M. Hummel
J. Hiscott
S.S. Wenzel
P. Lenz
M. Schneider
R. Küppers
C. Scheidereit
M. Giefing
R. Siebert
K. Rajewsky
G. Lenz
P.N. Cockerill
M. Janz
B. Dörken
C. Bonifer
S. Mathas

30. September 2014 in Nat Commun

Dendritic cell-mediated survival signals in Eμ-Myc B-cell lymphoma depend on the transcription factor C/EBPβ

A. Rehm
M. Gätjen
K. Gerlach
F. Scholz
A. Mensen
M. Gloger
K. Heinig
B. Lamprecht
S. Mathas
V. Bégay
A. Leutz
M. Lipp
B. Dörken
U.E. Höpken

26. September 2013 in Blood

IκB-ζ controls the constitutive NF-κB target gene network and survival of ABC DLBCL

H. Nogai
S.S. Wenzel
S. Hailfinger
M. Grau
E. Kaergel
V. Seitz
B. Wollert-Wulf
M. Pfeifer
A. Wolf
M. Frick
K. Dietze
H. Madle
A. Tzankov
M. Hummel
B. Dörken
C. Scheidereit
M. Janz
P. Lenz
M. Thome
G. Lenz

23. Juli 2013 in Proc Natl Acad Sci U S A

PTEN loss defines a PI3K/AKT pathway-dependent germinal center subtype of diffuse large B-cell lymphoma

M. Pfeifer
M. Grau
D. Lenze
S.S. Wenzel
A. Wolf
B. Wollert-Wulf
K. Dietze
H. Nogai
B. Storek
H. Madle
B. Dörken
M. Janz
S. Dirnhofer
P. Lenz
M. Hummel
A. Tzankov
G. Lenz

01. November 2012 in Nat Immunol

The cell-cycle regulator c-Myc is essential for the formation and maintenance of germinal centers

D.P. Calado
Y. Sasaki
S.A. Godinho
A. Pellerin
K. Köchert
B.P. Sleckman
I.M. de Alboran
M. Janz
S. Rodig
K. Rajewsky

01. April 2006 in Cell Death Differ

Loss of the tissue-specific proapoptotic BH3-only protein Nbk/Bik is a unifying feature of renal cell carcinoma

I. Sturm
C. Stephan
B. Gillissen
R. Siebert
M. Janz
S. Radetzki
K. Jung
S. Loening
B. Doerken
P.T. Daniel