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in PLoS Comput Biol

Multifunctional RNA-binding proteins influence mRNA abundance and translational efficiency of distinct sets of target genes

  • V. Schneider-Lunitz
  • J. Ruiz-Orera
  • N. Hubner
  • S. van Heesch
in Nat Commun

Rare variant analysis in eczema identifies exonic variants in DUSP1, NOTCH4 and SLC9A4

  • S. Grosche
  • I. Marenholz
  • J. Esparza-Gordillo
  • A. Arnau-Soler
  • E. Pairo-Castineira
  • F. Rüschendorf
  • T.S. Ahluwalia
  • C. Almqvist
  • A. Arnold
  • H. Baurecht
  • H. Bisgaard
  • K. Bønnelykke
  • S.J. Brown
  • M. Bustamante
  • J.A. Curtin
  • A. Custovic
  • S.C. Dharmage
  • A. Esplugues
  • M. Falchi
  • D. Fernandez-Orth
  • M.A.R. Ferreira
  • A. Franke
  • S. Gerdes
  • C. Gieger
  • H. Hakonarson
  • P.G. Holt
  • G. Homuth
  • N. Hubner
  • P.G. Hysi
  • M.R. Jarvelin
  • R. Karlsson
  • G.H. Koppelman
  • S. Lau
  • M. Lutz
  • P.K.E. Magnusson
  • G.B. Marks
  • M. Müller-Nurasyid
  • M.M. Nöthen
  • L. Paternoster
  • C.E. Pennell
  • A. Peters
  • K. Rawlik
  • C.F. Robertson
  • E. Rodriguez
  • S. Sebert
  • A. Simpson
  • P.M.A. Sleiman
  • M. Standl
  • D. Stölzl
  • K. Strauch
  • A. Szwajda
  • A. Tenesa
  • P.J. Thompson
  • V. Ullemar
  • A. Visconti
  • J.M. Vonk
  • C.A. Wang
  • S. Weidinger
  • M. Wielscher
  • C.L. Sargent
  • C.J. Xu
  • Y.A. Lee
in Biomolecules

Vascular tissue specific miRNA profiles reveal novel correlations with risk factors in coronary artery disease

  • K. Neiburga
  • B. Vilne
  • S. Bauer
  • D. Bongiovanni
  • T. Ziegler
  • M. Lachmann
  • S. Wengert
  • J. Hawe
  • U. Güldener
  • A. Westerlund
  • L. Li
  • S. Pang
  • C. Yang
  • K. Saar
  • N. Huebner
  • L. Maegdefessel
  • R. Lange
  • M. Krane
  • H. Schunkert
  • M. von Scheidt
in JCI Insight

Self-sustaining interleukin-8 loops drive a prothrombotic neutrophil phenotype in severe COVID-19

  • R. Kaiser
  • A. Leunig
  • K. Pekayvaz
  • O. Popp
  • M. Joppich
  • V. Polewka
  • R. Escaig
  • A. Anjum
  • M.L. Hoffknecht
  • C. Gold
  • S. Brambs
  • A. Engel
  • S. Stockhausen
  • V. Knottenberg
  • A. Titova
  • M. Haji
  • C. Scherer
  • M. Muenchhoff
  • J.C. Hellmuth
  • K. Saar
  • B. Schubert
  • A. Hilgendorff
  • C. Schulz
  • S. Kääb
  • R. Zimmer
  • N. Hübner
  • S. Massberg
  • P. Mertins
  • L. Nicolai
  • K. Stark
in Front Pediatr

Reduced systolic function and not genetic variants determine outcome in pediatric and adult left ventricular noncompaction cardiomyopathy

  • A. Schultze-Berndt
  • J. Kühnisch
  • C. Herbst
  • F. Seidel
  • N. Al-Wakeel-Marquard
  • J. Dartsch
  • S. Theisen
  • W. Knirsch
  • R. Jenni
  • M. Greutmann
  • E. Oechslin
  • F. Berger
  • S. Klaassen
in Circ Genom Precis Med

Pathogenic variants associated with dilated cardiomyopathy predict outcome in pediatric myocarditis

  • F. Seidel
  • M. Holtgrewe
  • N. Al-Wakeel-Marquard
  • B. Opgen-Rhein
  • J. Dartsch
  • C. Herbst
  • D. Beule
  • T. Pickardt
  • K. Klingel
  • D. Messroghli
  • F. Berger
  • S. Schubert
  • J. Kühnisch
  • S. Klaassen
in Stem Cell Res

Generation of bi-allelic MYBPC3 truncating mutant and isogenic control from an iPSC line of a patient with hypertrophic cardiomyopathy

  • N. Warnecke
  • B.M. Ulmer
  • S.D. Laufer
  • A. Shibamiya
  • E. Krämer
  • C. Neuber
  • S. Hanke
  • C. Behrens
  • M. Loos
  • J. Münch
  • J. Kühnisch
  • S. Klaassen
  • T. Eschenhagen
  • M. Patten-Hamel
  • L. Carrier
  • G. Mearini
in PLoS Genet

Integrative analysis of genomic variants reveals new associations of candidate haploinsufficient genes with congenital heart disease

  • E. Audain
  • A. Wilsdon
  • J. Breckpot
  • J.M. Izarzugaza
  • T.W. Fitzgerald
  • A.K. Kahlert
  • A. Sifrim
  • F. Wünnemann
  • Y. Perez-Riverol
  • H. Abdul-Khaliq
  • M. Bak
  • A.S. Bassett
  • W.D. Benson
  • F. Berger
  • I. Daehnert
  • K. Devriendt
  • S. Dittrich
  • P.E. Daubeney
  • V. Garg
  • K. Hackmann
  • K. Hoff
  • P. Hofmann
  • G. Dombrowsky
  • T. Pickardt
  • U. Bauer
  • B.D. Keavney
  • S. Klaassen
  • H.H. Kramer
  • C.R. Marshall
  • D.M. Milewicz
  • S. Lemaire
  • J.S. Coselli
  • M.E. Mitchell
  • A. Tomita-Mitchell
  • S.K. Prakash
  • K. Stamm
  • A.F.R. Stewart
  • C.K. Silversides
  • R. Siebert
  • B. Stiller
  • J.A. Rosenfeld
  • I. Vater
  • A.V. Postma
  • A. Caliebe
  • J.D. Brook
  • G. Andelfinger
  • M.E. Hurles
  • B. Thienpont
  • L.A. Larsen
  • M.P. Hitz
in Genome Biol

A trans locus causes a ribosomopathy in hypertrophic hearts that affects mRNA translation in a protein length-dependent fashion

  • F. Witte
  • J. Ruiz-Orera
  • C. Ciolli Mattioli
  • S. Blachut
  • E. Adami
  • J.F. Schulz
  • V. Schneider-Lunitz
  • O. Hummel
  • G. Patone
  • M.B. Mücke
  • Jan Šilhavý
  • M. Heinig
  • L. Bottolo
  • D. Sanchis
  • M. Vingron
  • M. Chekulaeva
  • M. Pravenec
  • N. Hubner
  • S. van Heesch
in Int J Cardiol

Diffuse myocardial fibrosis by T1 mapping is associated with heart failure in pediatric primary dilated cardiomyopathy

  • N. Al-Wakeel-Marquard
  • F. Seidel
  • C. Herbst
  • J. Kühnisch
  • T. Kuehne
  • F. Berger
  • S. Klaassen
  • D.R. Messroghli