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01. Dezember 2001 in Neurobiol Dis

Inhibition of polyglutamine aggregation in R6/2 HD brain slices-complex dose-response profiles

D.L. Smith
R. Portier
B. Woodman
E. Hockly
A. Mahal
W.E. Klunk
X.J. Li
E.E. Wanker
K.D. Murray
G.P. Bates

01. Oktober 2001 in Hum Mol Genet

Centrosome disorganization in fibroblast cultures derived from R6/2 Huntington's disease (HD) transgenic mice and HD patients

K. Sathasivam
B. Woodman
A. Mahal
F. Bertaux
E.E. Wanker
D.T. Shima
G.P. Bates

15. August 2001 in Hum Mol Genet

The huntingtin interacting protein HIP1 is a clathrin and alpha-adaptin-binding protein involved in receptor-mediated endocytosis

S. Waelter
E. Scherzinger
R. Hasenbank
E. Nordhoff
R. Lurz
H. Goehler
C. Gauss
K. Sathasivam
G.P. Bates
H. Lehrach
E.E. Wanker

01. Juni 2001 in Hum Mol Genet

Geldanamycin activates a heat shock response and inhibits huntingtin aggregation in a cell culture model of Huntington's disease

A. Sittler
R. Lurz
G. Lueder
J. Priller
H. Lehrach
M.K. Hayer-Hartl
F.U. Hartl
E.E. Wanker

01. Mai 2001 in Mol Biol Cell

Accumulation of mutant huntingtin fragments in aggresome-like inclusion bodies as a result of insufficient protein degradation

S. Waelter
A. Boeddrich
R. Lurz
E. Scherzinger
G. Lueder
H. Lehrach
E.E. Wanker

30. April 2001 in J Cell Biol

Lack of pericytes leads to endothelial hyperplasia and abnormal vascular morphogenesis

M. Hellström
H. Gerhardt
M. Kalén
X. Li
U. Eriksson
H. Wolburg
C. Betsholtz

01. Januar 2001 in Cytogenet Genome Res

Assignment of the huntingtin (Hdh) gene, the huntingtin associated protein (Hap1) gene, and the huntingtin interacting protein (Hip1) gene to rat chromosomes 14, 10, and 12 by radiation hybrid mapping and fluorescent in situ hybridization

H. Zimdahl
C. Goesele
G. Luetjens
F. Gruetzner
T. Kreitler
K. Voss
E.E. Wanker
M. Knoblauch

01. Januar 2001 in J Am Soc Nephrol

Role of mitogen-activated protein kinases in activation of human neutrophils by antineutrophil cytoplasmic antibodies

R. Kettritz
A. Schreiber
F.C. Luft
H. Haller

01. Dezember 1997 in Genomics

Localization of the human HIP1 gene close to the elastin (ELN) locus on 7q11.23

N. Wedemeyer
R. Peoples
H. Himmelbauer
H. Lehrach
U. Francke
E.E. Wanker

08. August 1997 in Cell

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

S.W. Davies
M. Turmaine
B.A. Cozens
M. DiFiglia
A.H. Sharp
C.A. Ross
E. Scherzinger
E.E. Wanker
L. Mangiarini
G.P. Bates