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18. Mai 2022 in Nat Commun

HDLBP binds ER-targeted mRNAs by multivalent interactions to promote protein synthesis of transmembrane and secreted proteins

U. Zinnall
M. Milek
I. Minia
C.H. Vieira-Vieira
S. Müller
G. Mastrobuoni
O.G. Hazapis
S. Del Giudice
D. Schwefel
N. Bley
F. Voigt
J.A. Chao
S. Kempa
S. Hüttelmaier
M. Selbach
M. Landthaler

18. Dezember 2021 in Metabolites

Optimized workflow for on-line derivatization for targeted metabolomics approach by gas chromatography-mass spectrometry

R. Fritsche-Guenther
Y. Gloaguen
A. Bauer
T. Opialla
S. Kempa
C.A. Fleming
H.P. Redmond
J.A. Kirwan

13. Juli 2021 in Circulation

Salt transiently inhibits mitochondrial energetics in mononuclear phagocytes

S. Geisberger
H. Bartolomaeus
P. Neubert
R. Willebrand
C. Zasada
T. Bartolomaeus
V. McParland
D. Swinnen
A. Geuzens
A. Maifeld
L. Krampert
M. Vogl
A. Mähler
N. Wilck
L. Marko
E. Tilic
S.K. Forslund
K.J. Binger
J. Stegbauer
R. Dechend
M. Kleinewietfeld
J. Jantsch
S. Kempa
D.N. Müller

30. Juni 2021 in J Enzyme Inhib Med Chem

Inhibiting PHGDH with NCT-503 reroutes glucose-derived carbons into the TCA cycle, independently of its on-target effect

B. Arlt
G. Mastrobuoni
J. Wuenschel
K. Astrahantseff
A. Eggert
S. Kempa
H.E. Deubzer

15. April 2021 in Int J Cancer

Abrogating GPT2 in triple negative breast cancer inhibits tumor growth and promotes autophagy

D. Mitra
S. Vega-Rubin-de-Celis
N. Royla
S. Bernhardt
H. Wilhelm
N. Tarade
G. Poschet
M. Buettner
I. Binenbaum
S. Borgoni
M. Vetter
E.J. Kantelhardt
C. Thomssen
A. Chatziioannou
R. Hell
S. Kempa
K. Müller-Decker
S. Wiemann

01. März 2021 in Int J Cancer

Inhibiting phosphoglycerate dehydrogenase counteracts chemotherapeutic efficacy against MYCN-amplified neuroblastoma

B. Arlt
C. Zasada
K. Baum
J. Wuenschel
G. Mastrobuoni
M. Lodrini
K. Astrahantseff
A. Winkler
J.H. Schulte
S. Finkler
M. Forbes
P. Hundsdoerfer
D. Guergen
J. Hoffmann
J. Wolf
A. Eggert
S. Kempa
H.E. Deubzer

19. Januar 2021 in Epigenetics Chromatin

Rbm10 facilitates heterochromatin assembly via the Clr6 HDAC complex

M. Weigt
Q. Gao
H. Ban
H. He
G. Mastrobuoni
S. Kempa
W. Chen
F. Li

12. November 2020 in Metabolites

Towards a more reliable identification of isomeric metabolites using pattern guided retention validation

T. Opialla
S. Kempa
M. Pietzke

18. August 2020 in Cell Rep

Interactome mapping provides a network of neurodegenerative disease proteins and uncovers widespread protein aggregation in affected brains

C. Haenig
N. Atias
A.K. Taylor
A. Mazza
M.H. Schaefer
J. Russ
S.P. Riechers
S. Jain
M. Coughlin
J.F. Fontaine
B.D. Freibaum
L. Brusendorf
M. Zenkner
P. Porras
M. Stroedicke
S. Schnoegl
K. Arnsburg
A. Boeddrich
L. Pigazzini
P. Heutink
J.P. Taylor
J. Kirstein
M.A. Andrade-Navarro
R. Sharan
E.E. Wanker

27. April 2020 in Nat Commun

Integrative functional genomics decodes herpes simplex virus 1

A.W. Whisnant
C.S. Jürges
T. Hennig
E. Wyler
B. Prusty
A.J. Rutkowski
A. L'hernault
L. Djakovic
M. Göbel
K. Döring
J. Menegatti
R. Antrobus
N.J. Matheson
F.W.H. Künzig
G. Mastrobuoni
C. Bielow
S. Kempa
C. Liang
T. Dandekar
R. Zimmer
M. Landthaler
F. Grässer
P.J. Lehner
C.C. Friedel
F. Erhard
L. Dölken