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/ Leukemia

The IL-15 cytokine system provides growth and survival signals in hodgkin lymphoma and enhances the inflammatory phenotype of HRS cells

  • K. Ullrich
  • F. Blumenthal-Barby
  • B. Lamprecht
  • K. Koechert
  • D. Lenze
  • M. Hummel
  • S. Mathas
  • B. Doerken
  • M. Janz
/ Blood

Essential role of IRF4 and MYC signaling for survival of anaplastic large cell lymphoma

  • A. Weilemann
  • M. Grau
  • T. Erdmann
  • O. Merkel
  • U. Sobhiafshar
  • I. Anagnostopoulos
  • M. Hummel
  • A. Siegert
  • C. Hayford
  • H. Madle
  • B. Wollert-Wulf
  • I. Fichtner
  • B. Dörken
  • S. Dirnhofer
  • S. Mathas
  • M. Janz
  • N.C.T. Emre
  • A. Rosenwald
  • G. Ott
  • P. Lenz
  • A. Tzankov
  • G. Lenz
/ Nat Immunol

The cell-cycle regulator c-Myc is essential for the formation and maintenance of germinal centers

  • D.P. Calado
  • Y. Sasaki
  • S.A. Godinho
  • A. Pellerin
  • K. Köchert
  • B.P. Sleckman
  • I.M. de Alboran
  • M. Janz
  • S. Rodig
  • K. Rajewsky
/ Br J Dermatol

The tumour suppressor p53 is frequently nonfunctional in Sezary syndrome

  • B. Lamprecht
  • S. Kreher
  • M. Moebs
  • W. Sterry
  • B. Doerken
  • M. Janz
  • C. Assaf
  • S. Mathas
/ Cell Cycle

Reprogramming of B lymphoid cells in human lymphoma pathogenesis

  • M. Janz
  • B. Doerken
  • S. Mathas
/ Cell Death Differ

Loss of the tissue-specific proapoptotic BH3-only protein Nbk/Bik is a unifying feature of renal cell carcinoma

  • I. Sturm
  • C. Stephan
  • B. Gillissen
  • R. Siebert
  • M. Janz
  • S. Radetzki
  • K. Jung
  • S. Loening
  • B. Doerken
  • P.T. Daniel
/ Blood

Classical Hodgkin lymphoma is characterized by high constitutive expression of activating transcription factor 3 (ATF3) which promotes viability of Hodgkin/Reed-Sternberg cells

  • M. Janz
  • M. Hummel
  • M. Truss
  • B. Wollert-Wulf
  • S. Mathas
  • K. Joehrens
  • C. Hagemeier
  • K. Bommert
  • H. Stein
  • B. Doerken
  • R.C. Bargou
/ Nat Immunol

Intrinsic inhibition of transcription factor E2A by HLH proteins ABF-1 and Id2 mediates reprogramming of neoplastic B cells in Hodgkin lymphoma

  • S. Mathas
  • M. Janz
  • F. Hummel
  • M. Hummel
  • B. Wollert-Wulf
  • S. Lusatis
  • I. Anagnostopoulos
  • A. Lietz
  • M. Sigvardsson
  • F. Jundt
  • K. Joehrens
  • K. Bommert
  • H. Stein
  • B. Doerken
/ J Exp Med

c-FLIP mediates resistance of Hodgkin/Reed-Sternberg cells to death receptor-induced apoptosis

  • S. Mathas
  • A. Lietz
  • I. Anagnostopoulos
  • F. Hummel
  • B. Wiesner
  • M. Janz
  • F. Jundt
  • B. Hirsch
  • K. Joehrens-Leder
  • H.P. Vornlocher
  • K. Bommert
  • H. Stein
  • B. Doerken
/ J Gene Med

Non-physiological overexpression of the low density lipoprotein receptor (LDLr) gene in the liver induces pathological intracellular lipid and cholesterol storage

  • G. Cichon
  • T.E. Willnow
  • S. Herwig
  • W. Uckert
  • P. Loeser
  • H.H. Schmidt
  • T. Benhidjeb
  • P.M. Schlag
  • F. Schnieders
  • D. Niedzielska
  • J. Heeren