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01. Mai 2007 in Br J Haematol

Loss of bHLH transcription factor E2A activity in primary effusion lymphoma confers resistance to apoptosis

A. Lietz
M. Janz
M. Sigvardsson
F. Jundt
B. Doerken
S. Mathas

01. April 2007 in Leukemia

Pharmacologic activation of p53-dependent and p53-independent apoptotic pathways in Hodgkin/Reed-Sternberg cells

M. Janz
T. Stuehmer
L.T. Vassilev
R.C. Bargou

15. Mai 2006 in Cell Cycle

Reprogramming of B lymphoid cells in human lymphoma pathogenesis

M. Janz
B. Doerken
S. Mathas

01. April 2006 in Cell Death Differ

Loss of the tissue-specific proapoptotic BH3-only protein Nbk/Bik is a unifying feature of renal cell carcinoma

I. Sturm
C. Stephan
B. Gillissen
R. Siebert
M. Janz
S. Radetzki
K. Jung
S. Loening
B. Doerken
P.T. Daniel

15. März 2006 in Blood

Classical Hodgkin lymphoma is characterized by high constitutive expression of activating transcription factor 3 (ATF3) which promotes viability of Hodgkin/Reed-Sternberg cells

M. Janz
M. Hummel
M. Truss
B. Wollert-Wulf
S. Mathas
K. Joehrens
C. Hagemeier
K. Bommert
H. Stein
B. Doerken
R.C. Bargou

01. Februar 2006 in Nat Immunol

Intrinsic inhibition of transcription factor E2A by HLH proteins ABF-1 and Id2 mediates reprogramming of neoplastic B cells in Hodgkin lymphoma

S. Mathas
M. Janz
F. Hummel
M. Hummel
B. Wollert-Wulf
S. Lusatis
I. Anagnostopoulos
A. Lietz
M. Sigvardsson
F. Jundt
K. Joehrens
K. Bommert
H. Stein
B. Doerken

25. August 2005 in Blood

Elevated NF-kappaB p50 complex formation and Bcl-3 expression in classical Hodgkin, anaplastic large cell, and other peripheral T-cell lymphomas

S. Mathas
K. Joehrens
S. Joos
A. Lietz
F. Hummel
M. Janz
F. Jundt
I. Anagnostopoulos
K. Bommert
P. Lichter
H. Stein
C. Scheidereit
B. Doerken

01. Januar 2005 in Blood

Immunomodulatory derivative of thalidomide (IMiD CC-4047) induces a shift in lineage commitment by suppressing erythropoiesis and promoting myelopoiesis

K.R. Koh
M. Janz
M.Y. Mapara
B. Lemke
D. Stirling
B. Doerken
M. Zenke
S. Lentzsch

19. April 2004 in J Exp Med

c-FLIP mediates resistance of Hodgkin/Reed-Sternberg cells to death receptor-induced apoptosis

S. Mathas
A. Lietz
I. Anagnostopoulos
F. Hummel
B. Wiesner
M. Janz
F. Jundt
B. Hirsch
K. Joehrens-Leder
H.P. Vornlocher
K. Bommert
H. Stein
B. Doerken

01. Februar 2004 in J Gene Med

Non-physiological overexpression of the low density lipoprotein receptor (LDLr) gene in the liver induces pathological intracellular lipid and cholesterol storage

G. Cichon
T.E. Willnow
S. Herwig
W. Uckert
P. Loeser
H.H. Schmidt
T. Benhidjeb
P.M. Schlag
F. Schnieders
D. Niedzielska
J. Heeren