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Designer T cells - New possibilities for immunotherapy of cancer [Designer-T-Zellen - neue Möglichkeiten für die Immuntherapie von Krebs]

  • M. Leisegang
  • W. Uckert
in Curr Opin Immunol

Targeting cancer-specific mutations by T cell receptor gene therapy

  • T. Blankenstein
  • M. Leisegang
  • W. Uckert
  • H. Schreiber
in Nat Biotechnol

Identification of human T-cell receptors with optimal affinity to cancer antigens using antigen-negative humanized mice

  • M. Obenaus
  • C. Leitão
  • M. Leisegang
  • X. Chen
  • I. Gavvovidis
  • P. van der Bruggen
  • W. Uckert
  • D.J. Schendel
  • T. Blankenstein
in PLoS ONE

Codon optimization of the human papillomavirus E7 oncogene induces a CD8(+) T cell response to a cryptic epitope not harbored by wild-type E7

  • F.K.M. Lorenz
  • S. Wilde
  • K. Voigt
  • E. Kieback
  • B. Mosetter
  • D.J. Schendel
  • W. Uckert
in J Virol

Protective capacity of virus-specific T cell receptor (TCR)-transduced CD8 T cells in vivo

  • K. Mueller
  • A. von Maessenhausen
  • U. Aichele
  • L. Staerck
  • M. Leisegang
  • W. Uckert
  • H. Pircher
in J Immunol

Human antitumor CD8+ T cells producing Th1 polycytokines show superior antigen sensitivity and tumor recognition

  • S. Wilde
  • D. Sommermeyer
  • M. Leisegang
  • B. Frankenberger
  • B. Mosetter
  • W. Uckert
  • D.J. Schendel
in Blood

TCR-transgenic lymphocytes specific for HMMR/Rhamm limit tumor outgrowth in vivo

  • S. Spranger
  • I. Jeremias
  • S. Wilde
  • M. Leisegang
  • L. Staerck
  • B. Mosetter
  • W. Uckert
  • M.H.M. Heemskerk
  • D.J. Schendel
  • B. Frankenberger