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in Clin Cancer Res

Eradication of large solid tumors by gene therapy with a T cell receptor targeting a single cancer-specific point mutation

  • M. Leisegang
  • B. Engels
  • K. Schreiber
  • P.Y. Yew
  • K. Kiyotani
  • C. Idel
  • A. Arina
  • J. Duraiswamy
  • R.R. Weichselbaum
  • W. Uckert
  • Y. Nakamura
  • H. Schreiber
in Sci Rep

Proteasomes generate spliced epitopes by two different mechanisms and as efficiently as non-spliced epitopes

  • F. Ebstein
  • K. Textoris-Taube
  • C. Keller
  • R. Golnik
  • N. Vigneron
  • B.J. Van den Eynde
  • B. Schuler-Thurner
  • D. Schadendorf
  • F.K.M. Lorenz
  • W. Uckert
  • S. Urban
  • A. Lehmann
  • N. Albrecht-Koepke
  • K. Janek
  • P. Henklein
  • A. Niewienda
  • P.M. Kloetzel
  • M. Mishto
in J Clin Invest

Targeting human melanoma neoantigens by T cell receptor gene therapy

  • M. Leisegang
  • T. Kammertoens
  • W. Uckert
  • T. Blankenstein
in BIOspektrum

Designer T cells - New possibilities for immunotherapy of cancer [Designer-T-Zellen - neue Möglichkeiten für die Immuntherapie von Krebs]

  • M. Leisegang
  • W. Uckert
in Curr Opin Immunol

Targeting cancer-specific mutations by T cell receptor gene therapy

  • T. Blankenstein
  • M. Leisegang
  • W. Uckert
  • H. Schreiber
in Nat Biotechnol

Identification of human T-cell receptors with optimal affinity to cancer antigens using antigen-negative humanized mice

  • M. Obenaus
  • C. Leitão
  • M. Leisegang
  • X. Chen
  • I. Gavvovidis
  • P. van der Bruggen
  • W. Uckert
  • D.J. Schendel
  • T. Blankenstein
in PLoS ONE

Codon optimization of the human papillomavirus E7 oncogene induces a CD8(+) T cell response to a cryptic epitope not harbored by wild-type E7

  • F.K.M. Lorenz
  • S. Wilde
  • K. Voigt
  • E. Kieback
  • B. Mosetter
  • D.J. Schendel
  • W. Uckert