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18. Dezember 2021 in Metabolites

Optimized workflow for on-line derivatization for targeted metabolomics approach by gas chromatography-mass spectrometry

R. Fritsche-Guenther
Y. Gloaguen
A. Bauer
T. Opialla
S. Kempa
C.A. Fleming
H.P. Redmond
J.A. Kirwan

01. Dezember 2021 in J Cachexia Sarcopenia Muscle

Inhibition of the NLRP3/IL-1β axis protects against sepsis-induced cardiomyopathy

K. Busch
M. Kny
N. Huang
T.E. Klassert
M. Stock
A. Hahn
S. Graeger
M. Todiras
S. Schmidt
B. Chamling
M. Willenbrock
S. Groß
D. Biedenweg
A. Heuser
C. Scheidereit
C. Butter
S.B. Felix
O. Otto
F.C. Luft
H. Slevogt
J. Fielitz

01. November 2021 in Development

NF-κB determines Paneth versus goblet cell fate decision in the small intestine

C. Brischetto
K. Krieger
C. Klotz
I. Krahn
S. Kunz
M. Kolesnichenko
P. Mucka
J. Heuberger
C. Scheidereit
R. Schmidt-Ullrich

13. Juli 2021 in Circulation

Salt transiently inhibits mitochondrial energetics in mononuclear phagocytes

S. Geisberger
H. Bartolomaeus
P. Neubert
R. Willebrand
C. Zasada
T. Bartolomaeus
V. McParland
D. Swinnen
A. Geuzens
A. Maifeld
L. Krampert
M. Vogl
A. Mähler
N. Wilck
L. Marko
E. Tilic
S.K. Forslund
K.J. Binger
J. Stegbauer
R. Dechend
M. Kleinewietfeld
J. Jantsch
S. Kempa
D.N. Müller

30. Juni 2021 in J Enzyme Inhib Med Chem

Inhibiting PHGDH with NCT-503 reroutes glucose-derived carbons into the TCA cycle, independently of its on-target effect

B. Arlt
G. Mastrobuoni
J. Wuenschel
K. Astrahantseff
A. Eggert
S. Kempa
H.E. Deubzer

15. April 2021 in Int J Cancer

Abrogating GPT2 in triple negative breast cancer inhibits tumor growth and promotes autophagy

D. Mitra
S. Vega-Rubin-de-Celis
N. Royla
S. Bernhardt
H. Wilhelm
N. Tarade
G. Poschet
M. Buettner
I. Binenbaum
S. Borgoni
M. Vetter
E.J. Kantelhardt
C. Thomssen
A. Chatziioannou
R. Hell
S. Kempa
K. Müller-Decker
S. Wiemann

15. März 2021 in EMBO J

Transcriptional repression of NFKBIA triggers constitutive IKK- and proteasome-independent p65/RelA activation in senescence

M. Kolesnichenko
N. Mikuda
U.E. Höpken
E. Kärgel
B. Uyar
A.B. Tufan
M. Milanovic
W. Sun
I. Krahn
K. Schleich
L. von Hoff
M. Hinz
M. Willenbrock
S. Jungmann
A. Akalin
S. Lee
R. Schmidt-Ullrich
C.A. Schmitt
C. Scheidereit

01. März 2021 in Int J Cancer

Inhibiting phosphoglycerate dehydrogenase counteracts chemotherapeutic efficacy against MYCN-amplified neuroblastoma

B. Arlt
C. Zasada
K. Baum
J. Wuenschel
G. Mastrobuoni
M. Lodrini
K. Astrahantseff
A. Winkler
J.H. Schulte
S. Finkler
M. Forbes
P. Hundsdoerfer
D. Guergen
J. Hoffmann
J. Wolf
A. Eggert
S. Kempa
H.E. Deubzer

19. Januar 2021 in Epigenetics Chromatin

Rbm10 facilitates heterochromatin assembly via the Clr6 HDAC complex

M. Weigt
Q. Gao
H. Ban
H. He
G. Mastrobuoni
S. Kempa
W. Chen
F. Li

12. November 2020 in Metabolites

Towards a more reliable identification of isomeric metabolites using pattern guided retention validation

T. Opialla
S. Kempa
M. Pietzke