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in Leukemia

Intracellular expression of FLT3 in Purkinje cells: implications for adoptive T-cell therapies

N. Çakmak-Görür et al.
in J Clin Invest

Effective NY-ESO-1-specific MHC II-restricted T cell receptors from antigen-negative hosts enhance tumor regression

L. Poncette et al.
in Cancer Immunol Res

Mapping the MHC class I spliced immunopeptidome of cancer cells

J. Liepe et al.
in Hum Gene Ther

Unbiased identification of T cell receptors targeting immunodominant peptide-MHC complexes for T cell receptor immunotherapy

F.K.M. Lorenz et al.
in Sci Rep

Proteasomes generate spliced epitopes by two different mechanisms and as efficiently as non-spliced epitopes

F. Ebstein et al.
in Bioorg Med Chem

Light-switched inhibitors of protein tyrosine phosphatase PTP1B based on phosphonocarbonyl phenylalanine as photoactive phosphotyrosine mimetic

S. Wagner et al.
in EMBO J

Shp2 signaling suppresses senescence in PyMT-induced mammary gland cancer in mice

L. Lan et al.
in ChemMedChem

Selective inhibitors of the protein tyrosine phosphatase SHP2 block cellular motility and growth of cancer cells in vitro and in vivo

S. Grosskopf et al.
in PLoS ONE

Codon optimization of the human papillomavirus E7 oncogene induces a CD8(+) T cell response to a cryptic epitope not harbored by wild-type E7

F.K.M. Lorenz et al.
in Bioorg Med Chem

Flexible, polymer-supported synthesis of sphingosine derivatives provides ceramides with enhanced biological activity

A. El-Dahshan et al.