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10. Dezember 2020 in J Med Chem

From pyrazolones to azaindoles: evolution of active-site SHP2 inhibitors based on scaffold hopping and bioisosteric replacement

Y. Mostinski
G.J.J.E. Heynen
M.P. López-Alberca
J. Paul
S. Miksche
S. Radetzki
D. Schaller
E. Shanina
C. Seyffarth
Y. Kolomeets
N. Ziebart
J. de Schryver
S. Oestreich
M. Neuenschwander
Y. Roske
U. Heinemann
C. Rademacher
A. Volkamer
J.P. von Kries
W. Birchmeier
M. Nazaré

01. Mai 2015 in ChemMedChem

Selective inhibitors of the protein tyrosine phosphatase SHP2 block cellular motility and growth of cancer cells in vitro and in vivo

S. Grosskopf
C. Eckert
C. Arkona
S. Radetzki
K. Böhm
U. Heinemann
G. Wolber
J.P. von Kries
W. Birchmeier
J. Rademann

01. Februar 2014 in Genes Dev

Activation of MAPK overrides the termination of myelin growth and replaces Nrg1/ErbB3 signals during Schwann cell development and myelination

M.E. Sheean
E. McShane
C. Cheret
J. Walcher
T. Müller
A. Wulf-Goldenberg
S. Hoelper
A.N. Garratt
M. Krüger
K. Rajewsky
D. Meijer
W. Birchmeier
G.R. Lewin
M. Selbach
C. Birchmeier

01. Mai 2012 in PLoS Biol

A genetic basis for mechanosensory traits in humans

H. Frenzel
J. Bohlender
K. Pinsker
B. Wohlleben
J. Tank
S.G. Lechner
D. Schiska
T. Jaijo
F. Rueschendorf
K. Saar
J. Jordan
J.M. Millan
M. Gross
G.R. Lewin

06. Dezember 2007 in Neuron

Nociceptive tuning by stem cell factor/c-Kit signaling

N. Milenkovic
C. Frahm
M. Gassmann
C. Griffel
B. Erdmann
C. Birchmeier
G.R. Lewin
A.N. Garratt

01. November 2004 in Nat Genet

Mutations in the desmosomal protein plakophilin-2 are common in arrhythmogenic right ventricular cardiomyopathy

B. Gerull
A. Heuser
T. Wichter
M. Paul
C.T. Basson
D.A. McDermott
B.B. Lerman
S.M. Markowitz
P.T. Ellinor
C.A. MacRae
S. Peters
K.S. Grossmann
J. Drenckhahn
B. Michely
S. Sasse-Klaassen
W. Birchmeier
R. Dietz
G. Breithardt
E. Schulze-Bahr
L. Thierfelder