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in ChemMedChem

Selective inhibitors of the protein tyrosine phosphatase SHP2 block cellular motility and growth of cancer cells in vitro and in vivo

  • S. Grosskopf
  • C. Eckert
  • C. Arkona
  • S. Radetzki
  • K. Böhm
  • U. Heinemann
  • G. Wolber
  • J.P. von Kries
  • W. Birchmeier
  • J. Rademann
in Genes Dev

Activation of MAPK overrides the termination of myelin growth and replaces Nrg1/ErbB3 signals during Schwann cell development and myelination

  • M.E. Sheean
  • E. McShane
  • C. Cheret
  • J. Walcher
  • T. Müller
  • A. Wulf-Goldenberg
  • S. Hoelper
  • A.N. Garratt
  • M. Krüger
  • K. Rajewsky
  • D. Meijer
  • W. Birchmeier
  • G.R. Lewin
  • M. Selbach
  • C. Birchmeier
in PLoS Biol

A genetic basis for mechanosensory traits in humans

  • H. Frenzel
  • J. Bohlender
  • K. Pinsker
  • B. Wohlleben
  • J. Tank
  • S.G. Lechner
  • D. Schiska
  • T. Jaijo
  • F. Rueschendorf
  • K. Saar
  • J. Jordan
  • J.M. Millan
  • M. Gross
  • G.R. Lewin
in Neuron

Nociceptive tuning by stem cell factor/c-Kit signaling

  • N. Milenkovic
  • C. Frahm
  • M. Gassmann
  • C. Griffel
  • B. Erdmann
  • C. Birchmeier
  • G.R. Lewin
  • A.N. Garratt
in Nat Genet

Mutations in the desmosomal protein plakophilin-2 are common in arrhythmogenic right ventricular cardiomyopathy

  • B. Gerull
  • A. Heuser
  • T. Wichter
  • M. Paul
  • C.T. Basson
  • D.A. McDermott
  • B.B. Lerman
  • S.M. Markowitz
  • P.T. Ellinor
  • C.A. MacRae
  • S. Peters
  • K.S. Grossmann
  • J. Drenckhahn
  • B. Michely
  • S. Sasse-Klaassen
  • W. Birchmeier
  • R. Dietz
  • G. Breithardt
  • E. Schulze-Bahr
  • L. Thierfelder