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02. Dezember 2020 in Mol Ther

CRISPR/Cas9-mediated ELANE mutation correction in hematopoietic stem and progenitor cells to treat Severe Congenital Neutropenia

N.T. Tran
R. Graf
A. Wulf-Goldenberg
M. Stecklum
G. Strauß
R. Kühn
C. Kocks
K. Rajewsky
V.T. Chu

23. Oktober 2020 in BMC Biotechnol

Enhancement of CRISPR-Cas9 induced precise gene editing by targeting Histone H2A-K15 ubiquitination

S. Bashir
T. Dang
J. Rossius
J. Wolf
R. Kuehn

01. Oktober 2019 in Nat Neurosci

Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity

C. Fecher
L. Trovò
S.A. Müller
N. Snaidero
J. Wettmarshausen
S. Heink
O. Ortiz
I. Wagner
R. Kühn
J. Hartmann
R.M. Karl
A. Konnerth
T. Korn
W. Wurst
D. Merkler
S.F. Lichtenthaler
F. Perocchi
T. Misgeld

24. September 2019 in Cell Rep

Efficient CRISPR/Cas9-mediated gene knockin in mouse hematopoietic stem and progenitor cells

N.T. Tran
T. Sommermann
R. Graf
J. Trombke
J. Pempe
K. Petsch
R. Kühn
K. Rajewsky
V.T. Chu

01. Juli 2019 in Front Genet

Efficient and precise CRISPR/Cas9-mediated MECP2 modifications in human-induced pluripotent stem cells

T.T.H. Le
N.T. Tran
T.M.L. Dao
D.D. Nguyen
H.D. Do
T.L. Ha
R. Kühn
T.L. Nguyen
K. Rajewsky
V.T. Chu

13. Juni 2019 in Blood

Chronic CD30-signaling in B cells results in lymphomagenesis by driving the expansion of plasmablasts and B1 cells

S.A. Sperling
P. Fiedler
M. Lechner
A. Pollithy
S. Ehrenberg
A.I. Schiefer
L. Kenner
A. Feuchtinger
R. Kühn
G. Swinerd
M. Schmidt-Supprian
L.J. Strobl
U. Zimber-Strobl

01. Mai 2019 in Genes Dev

Oscillations of MyoD and Hes1 proteins regulate the maintenance of activated muscle stem cells

I. Lahmann
D. Bröhl
T. Zyrianova
A. Isomura
M.T. Czajkowski
V. Kapoor
J. Griger
P.L. Ruffault
D. Mademtzoglou
P.S. Zammit
T. Wunderlich
S. Spuler
R. Kühn
S. Preibisch
J. Wolf
R. Kageyama
C. Birchmeier

30. April 2019 in Front Genet

Enhancement of precise gene editing by the association of Cas9 with homologous recombination factors

N.T. Tran
S. Bashir
X. Li
J. Rossius
V.T. Chu
K. Rajewsky
R. Kühn

14. März 2019 in Sci Rep

The Parkinson's disease-linked Leucine-rich repeat kinase 2 (LRRK2) is required for insulin-stimulated translocation of GLUT4

N. Funk
M. Munz
T. Ott
K. Brockmann
A. Wenninger-Weinzierl
R. Kühn
D. Vogt-Weisenhorn
F. Giesert
W. Wurst
T. Gasser
S. Biskup

01. Januar 2019 in Methods Mol Biol

Efficient gene editing of human induced pluripotent stem cells using CRISPR/Cas9

S. Yumlu
S. Bashir
J. Stumm
R. Kühn