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in Development

Identification of disease-relevant modulators of the SHH pathway in the developing brain

  • N. Mecklenburg
  • I. Kowalczyk
  • F. Witte
  • J. Görne
  • A. Laier
  • T.M. Mamo
  • H. Gonschior
  • M. Lehmann
  • M. Richter
  • A. Sporbert
  • B. Purfürst
  • N. Hübner
  • A. Hammes
in Genome Biol

A trans locus causes a ribosomopathy in hypertrophic hearts that affects mRNA translation in a protein length-dependent fashion

  • F. Witte
  • J. Ruiz-Orera
  • C. Ciolli Mattioli
  • S. Blachut
  • E. Adami
  • J.F. Schulz
  • V. Schneider-Lunitz
  • O. Hummel
  • G. Patone
  • M.B. Mücke
  • Jan Šilhavý
  • M. Heinig
  • L. Bottolo
  • D. Sanchis
  • M. Vingron
  • M. Chekulaeva
  • M. Pravenec
  • N. Hubner
  • S. van Heesch
in eLife

A human ESC-based screen identifies a role for the translated lncRNA LINC00261 in pancreatic endocrine differentiation

  • B. Gaertner
  • S. van Heesch
  • V. Schneider-Lunitz
  • J.F. Schulz
  • F. Witte
  • S. Blachut
  • S. Nguyen
  • R. Wong
  • I. Matta
  • N. Hübner
  • M. Sander
in Aging Cell

The conserved histone chaperone LIN-53 is required for normal lifespan and maintenance of muscle integrity in Caenorhabditis elegans.

  • S. Müthel
  • B. Uyar
  • M. He
  • A. Krause
  • B. Vitrinel
  • S. Bulut
  • D. Vasiljevic
  • I. Marchal
  • S. Kempa
  • A. Akalin
  • B. Tursun
in Circulation

Widespread translational control of fibrosis in the human heart by RNA-binding proteins

  • S. Chothani
  • S. Schäfer
  • E. Adami
  • S. Viswanathan
  • A.A. Widjaja
  • S.R. Langley
  • J. Tan
  • M. Wang
  • N.M. Quaife
  • C.J. Pua
  • G. D'Agostino
  • S.G. Shekeran
  • B.L. George
  • S. Lim
  • E.Y. Cao
  • S. van Heesch
  • F. Witte
  • L.E. Felkin
  • E.G. Christodoulou
  • J. Dong
  • S. Blachut
  • G. Patone
  • P.J.R. Barton
  • N. Hubner
  • S.A. Cook
  • O.J.L. Rackham
in Cell

The translational landscape of the human heart

  • S. van Heesch
  • F. Witte
  • V. Schneider-Lunitz
  • J.F. Schulz
  • E. Adami
  • A. Faber
  • M. Kirchner
  • H. Maatz
  • S. Blachut
  • C.L. Sandmann
  • M. Kanda
  • C.L. Worth
  • S. Schafer
  • L. Calviello
  • R. Merriott
  • G. Patone
  • O. Hummel
  • E. Wyler
  • B. Obermayer
  • M. Mücke
  • E.L. Lindberg
  • F. Trnka
  • S. Memczak
  • M. Schilling
  • L.E. Felkin
  • P.J.R. Barton
  • N.M. Quaife
  • K. Vanezis
  • S. Diecke
  • M. Mukai
  • N. Mah
  • S.J. Oh
  • A. Kurtz
  • C. Schramm
  • D. Schwinge
  • M. Sebode
  • M. Harakalova
  • F.W. Asselbergs
  • A. Vink
  • R.A. de Weger
  • S. Viswanathan
  • A.A. Widjaja
  • A. Gärtner-Rommel
  • H. Milting
  • C. Dos Remedios
  • C. Knosalla
  • P. Mertins
  • M. Landthaler
  • M. Vingron
  • W.A. Linke
  • J.G. Seidman
  • C.E. Seidman
  • N. Rajewsky
  • U. Ohler
  • S.A. Cook
  • N. Hubner
in Nucleic Acids Res

HOT or not: examining the basis of high-occupancy target regions

  • K. Wreczycka
  • V. Franke
  • B. Uyar
  • R. Wurmus
  • S. Bulut
  • B. Tursun
  • A. Akalin
in Cell

Mutations in disordered regions can cause disease by creating dileucine motifs

  • K. Meyer
  • M. Kirchner
  • B. Uyar
  • J.Y. Cheng
  • G. Russo
  • L.R. Hernandez-Miranda
  • A. Szymborska
  • H. Zauber
  • I.M. Rudolph
  • T.E. Willnow
  • A. Akalin
  • V. Haucke
  • H. Gerhardt
  • C. Birchmeier
  • R. Kühn
  • M. Krauss
  • S. Diecke
  • J.M. Pascual
  • M. Selbach
in Dev Cell

FACT sets a barrier for cell fate reprogramming in Caenorhabditis elegans and human cells

  • E. Kolundzic
  • A. Ofenbauer
  • S.I. Bulut
  • B. Uyar
  • G. Baytek
  • A. Sommermeier
  • S. Seelk
  • M. He
  • A. Hirsekorn
  • D. Vucicevic
  • A. Akalin
  • S. Diecke
  • S.A. Lacadie
  • B. Tursun
in Diabetes

Nrf2-mediated antioxidant defense and peroxiredoxin 6 are linked to biosynthesis of palmitic acid ester of 9-hydroxystearic acid

  • O. Kuda
  • M. Brezinova
  • J. Silhavy
  • V. Landa
  • V. Zidek
  • C. Dodia
  • F. Kreuchwig
  • M. Vrbacky
  • L. Balas
  • T. Durand
  • N. Hübner
  • A.B. Fisher
  • J. Kopecky
  • M. Pravenec