News

After spending many years researching together, a group of scientists has founded CARTemis Therapeutics, a spin-off from the Max Delbrück Center. Uta Höpken, Armin Rehm, Anthea Wirges, and Mario Bunse want to use novel CAR T-cell therapies to help patients with cancers that are currently untreatable.

Cryo-electron microscopy allows structural biologists to look at the most minute building blocks of life. We celebrated the opening of the joint Core Facility and the corresponding research building of Charité – Universitätsmedizin Berlin and the Max Delbrück Center with a symposium.

Whether aggressive cancer cells can spread unchecked depends, to no small degree, on their cellular neighborhood. Fabian Coscia wants to analyze exactly what happens at the proteome level during this interaction. He has now been selected for a €1 million-plus grant from the European Research Council (ERC) to pursue this research.

Internationally renowned for pioneering achievements and geared to inter-institutional cooperation: 22 research groups at the Berlin Institute for Medical Systems Biology in the Max Delbrück Center (MDC-BIMSB) explore how genes regulate life. It is now celebrating its 15th birthday.

The Max Delbrück Center has revised its guidelines for good scientific practice. Based on these guidelines, the institute commits its scientists to integrity and honesty in their research, exemplary leadership and training, as well as proper attribution of intellectual property.

Bartter syndrome type 3 is the result of several structural variants in the genome. By using long-read sequencing, Janine Altmüller and her team from the Max Delbrück Center, the BIH and University Hospital Cologne mapped out the rare disease in unprecedented detail. They have now reported their findings in “Genome Medicine.”

Cancer cells are capable of escaping chemotherapy and radiotherapy by activating a signaling pathway that prevents them from dying. Researchers led by Claus Scheidereit at the Max Delbrück Center have now described in Cell Chemical Biology two new compounds that block this escape route.

The mucus in the airways is not as sticky, inflammation in the lungs significantly reduced: the positive effects of triple combination therapy in patients with cystic fibrosis are supported by researchers from Charité and the Max Delbrück Center in the “European Respiratory Journal”.

An international research team, including Achim Leutz of the Max Delbrück Center, has discovered that a specific protein controls the conversion of immune cells. If it were possible to intervene in this process, the development of cancer could be prevented.

The Max Delbrück Center in Berlin and Heidelberg University will found a new Helmholtz Institute for Translational AngioCardioScience (HI-TAC) in Mannheim and Heidelberg. The Helmholtz Senate voted in favor of the institute, which will integrate vascular biomedicine, systems biology and heart research.