News

Researchers from the MDC have developed a new tool that makes it easier to maximize the power of deep learning for studying genomics. They describe the new approach, Janggu, in the journal Nature Communications.

Setting out to identify all proteins that make up the sarcomere, the basic contractile unit of muscle cells, resulted in an unexpected revelation, providing experimental evidence that helps explain a fundamental mystery about how muscles work. The research was published in Nature Communications.

MDC researcher Jan Philipp Junker and his collaborator Maria Colomé-Tatché at Helmholtz Center Munich have received a €200,000 grant to improve big data processing to better understand how gene networks are wired together during development and disease.

Genome researchers have come together to launch the German COVID-19 OMICS Initiative (DeCOI). DeCOI combines the expertise of more than 22 institutions from across Germany to make a scientific contribution to fighting the COVID-19 pandemic.

The LabHive digital platform aims to provide necessary resources to diagnostic centres to enable more tests for SARS-CoV-2. Tobias Opialla from the MDC is one of 15 volunteers who has been involved in the project since the #WirvsVirus Hackathon organized by the German government.

Two specific cell types in the nose have been identified as likely initial infection points for the novel coronavirus that causes COVID-19. Using data from the Human Cell Atlas, scientists discovered that goblet and ciliated cells in the nose have high levels of the entry proteins that SARS-CoV-2 uses to get into our cells.

Strategies for treating multiple sclerosis have so far focused primarily on T and B cells. A group of MDC researchers has now unveiled a new approach in Nature Immunology – one that seeks to increase treatment effectiveness by selectively targeting another type of immune cell called monocytes.

Thomas Blankenstein receives an ERC Advanced grant for cancer research. The scientist wants to find out if T cells control the development of cancer by a process called immunosurveillance. For this purpose he now proposes a new research model.

In light of the pandemic, the Max Delbrück Center for Molecular Medicine (MDC) is pooling together its resources for projects that advance the understanding of SARS-CoV-2, while scaling down its regular research operations to a minimum. Here’s an overview of the MDC’s current collaborations and plans.

A protein in the cell envelope influences the rate of fatty acid uptake in cells. This is reported by MDC researchers in the journal PNAS. This process also appears to be altered in overweight people.