News

Neuroscientists Gary Lewin and James Poulet at the Max Delbrück Center for Molecular Medicine have won highly coveted and competitive ERC Advanced Grants to study pain and the neural mechanisms that underlie temperature perception.

Their research is outstanding, and they’re also committed to the Max Delbrück Center and engaged in our community — Manqiang Lin and Artsemi Yushkevich wrote the best papers in 2023; Hendrik Bartolomaeus, Eleonore Adami and Ulrike Löber received the Postdoc Awards for 2023.

The German Research Foundation (DFG) will fund single-cell scientist Simon Haas in its Heisenberg program. Therefore, the Berlin Institute of Health at Charité (BIH) is establishing a Heisenberg professorship in systems hematology. After five years, the BIH will make the professorship permanent.

Touch is a fundamental, yet scarcely understood, sense. Now, the team led by Gary Lewin at the Max Delbrück Center has discovered a second ion channel associated with touch perception. Elkin1 could be a target for pain therapy, the team writes in “Science”.

Special receptor cells under the skin enable us to feel pain and touch. But Schwann cells also play a key role in detecting such stimuli, researchers at the Max Delbrück Center report in “Nature Communications.” This discovery opens new avenues for pain therapy.

A new computer program allows scientists to design synthetic DNA segments that indicate, in real time, the state of cells. Reported by the Gargiulo lab in “Nature Communications”, it will be used to screen for anti-cancer or viral infections drugs, or to improve gene and cell-based immunotherapies.

The international BioRescue consortium in Berlin has announced that for the first time a rhino has successfully become pregnant following embryo transfer. This paves the way for using of the same method of reproductive medicine to save the northern white rhino from extinction.

Melissa Birol of the Max Delbrück Center is looking to understand early stages of Alzheimer’s disease. Her focus is on the interplay between the lipid metabolism of nerve cells and the spread of tau protein. The Alzheimer Research Initiative is funding her work with 193,500 euros.

In neuromuscular diseases, neurons and muscle cells stop communicating properly. Researchers led by Mina Gouti can now model this in 2D in a culture dish. Writing about their findings in “Nature Communications”, they say the new model promises to revolutionize high-throughput drug screening studies.

Working in Berlin-Mitte and New York – Lena Nitsch conducts research at both the MDC-BIMSB and New York University. For “We at the MDC”, the doctoral student discusses how it is to work in two labs, her experiences in the United States, and what she has learned through the “MDC-NYU PhD Exchange Program”.