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Science

How proteins reshape cell membranes

Small “bubbles” frequently form on membranes of cells and are taken up into their interior. The process involves EHD proteins – a focus of research by Oliver Daumke of the MDC. He and his team have now shed light on how these proteins assemble on the surface of a cell and reshape its membrane.
Cover-Art_Spagnoli
Science

Inducing an identity crisis in liver cells may help diabetics

It is now possible to reprogram cells from the liver into the precursor cells that give rise to the...
Klaus Rajewsky in the lab
Institute & Campus By Russell Hodge

Building "a small universe:" the very model of a laboratory

Klaus Rajewsky reflects on over 50 years of excellent research and the lab culture that made it possible
Structure model of the new protein complex
Press Release No. 45 Berlin

Disturbance wanted – Newly characterized protein interaction may help in search for new cancer-fighting drugs

Many proteins organize in so-called protein complexes, joining forces to fulfill certain tasks. The...
gutmann_potente
Press Release No. 44 Berlin

Three new guest scientists foster research at MDC and BIH

Excellent new people at the Max Delbrück Center: The Charité Foundation and the Einstein Foundation of Berlin are supporting three professors who will come to Berlin to collaborate with MDC groups under the framework of the Berlin Institute of Health (BIH). The support is part of the BIH strategy to bring findings from basic research more quickly into clinical practice.
Press Release No. 43 Berlin

The life cycle of proteins

What’s the life of a protein like? First, a blueprint is transcribed from a gene and eventually...
Press Release No. 40 Berlin

The life cycle of proteins

Throughout their lives, proteins have a plethora of different tasks and finally are being disposed...
Gunnar Dittmar
Science By Russell Hodge

The collaborator who couldn't say no - Gunnar Dittmar and the culture of mass spectrometry: past, present, and future

Bound for the Luxemburg Institute of Health, Gunnar Dittmar took a few minutes to look back on eight years as head of the Proteomics Core Facility at the MDC and BIH, and to discuss the near future of one of molecular biology's most important tools.
Keynote speaker Titia de Lange of the Rockefeller University, New York, presents her ideas in front of the audience at the symposium.
Science

Advancing the frontiers of DNA repair – together

How is our genome maintained and repaired? It's a crucial question – a number of genetic diseases and cancers can be traced to defects in the cellular mechanisms that repair DNA damage. The conference "Frontiers in DNA Repair," organized by MDC scientist Dr. Michela Di Virgilio, recently brought leading researchers on the topic to Berlin to discuss the latest developments in the field.
Science

Protein quality control in the cell: Waste removal more efficient than expected

Proteins perform so many vital tasks that without them, our bodies wouldn't function. In producing these molecules cells make a remarkable number of mistakes: about one third of all newly synthesized proteins are defective. A failure to recognize and eliminate them can lead to severe diseases. A team led by Prof. Thomas Sommer at the MDC has now gained new insights into the complex process of protein quality control in the cell.