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(29) Women in Science (30) Work and Family (9) Zeitzeugen (2) News (6) Press Release (4) 2017 (1) 2019 (1) 2020 (3) 2021 (2) 2022 (2) 2023 (1) 10 Results: Active Filter: Amyotrophic lateral sclerosis (ALS) Sort: Result score Newest to oldest Oldest to newest Press Release No. 3 January 24, 2023 Berlin ERC Proof of Concept Grant for Mina Gouti Organoids have to be fed and cared for continuously so that they can mature. So far, it is mostly a manual process – not suitable for industrial drug screening. Now, the European Research Council (ERC) has awarded Mina Gouti a Proof of Concept Grant to tackle scalability and reproducibility. Institute & Campus September 02, 2022 Heisenberg Program accepts RNA biologist Errors in cellular RNA metabolism are dangerous for nerve cells. For her work in this area, Marina Chekulaeva has now been accepted into the DFG Heisenberg program. Science February 23, 2022 The tissue engineer Mina Gouti uses stem cells to create three-dimensional cell structures called organoids that closely resemble some aspects of real human tissues. The organoids are well suited for testing new drugs to combat neuromuscular diseases and for developing personalized therapies to treat severely ill patients. Press Release No. 58 November 17, 2021 Berlin Genome folding in the mouse brain A team led by MDC researcher Ana Pombo has deciphered the 3D structure of the genome in three cell types of the mouse brain. They not only discovered specific folding patterns but also found that very long genes almost completely lose their compact folded structure when most at work, as they report in “Nature”. Science January 12, 2021 Dancing spaghetti on the brain In December 2020, biophysicist Melissa Birol joined the MDC as a new junior group leader to investigate the behavior and function of disordered proteins in brain cells. Press Release No. 55 December 09, 2020 Berlin Mina Gouti awarded ERC Consolidator Grant The European Research Council (ERC) awarded Dr. Mina Gouti a €2.8 million Consolidator Grant to further develop miniature neuromuscular organoids for studying neuromuscular development and diseases. It was the second honor in as many weeks; she was also named an EMBO Young Investigator for her work. Science September 30, 2020 Unusual suspects The NeuroNet1.0 interactome network reveals a wealth of novel proteins that could be involved in the development of neurodegenerative diseases. Professor Erich Wanker’s MDC research group recently published a paper on this topic in the journal Cell Reports. Press Release No. 2 January 16, 2020 Berlin Neuromuscular organoid: It’s contracting! MDC researchers established a new model to study neuromuscular development and disorders. For the first time two distinct human tissues co-developed in the lab from one progenitor cell type and self-organized into a complex, functional neuromuscular organoid. Science June 04, 2019 Growing mini-organs from stem cells During the "Long Night of Sciences" on June 15, visitors can see something that hardly anyone has seen before - simply because it is still so new: spinal cord neurons and skeletal muscle tissue that have been cultivated together from stem cells. Science October 26, 2017 The logistics of neuronal messenger RNAs Where proteins are localized within a cell is crucial to their proper function, especially in cells like neurons. It affects neuronal development and even learning and memory. A research team led by Marina Chekulaeva has for the first time systematically analyzed how this localization comes about. Their article appeared in Nature Communications.