Newsroom | Max Delbrück Center for Molecular Medicine

B2 cells in the spleen

February 14, 2019

On the origin of B1 cells

A new MDC study may resolve a decades-old debate in immunology: A team led by Prof. Klaus Rajewsky reports in Science that distinct progenitor cells are not required for the development of B1 cells. Instead, the team’s experiments show that a particular type of B-cell receptor can reprogram B2 cells into B1 cells, suggesting that B1 cells emerge as a consequence of their special B-cell receptors.

1st Immunology & Inflammation Conference - Poster

Institute & Campus February 12, 2019

“We’re expecting the world’s elite immunology researchers”

In late February, the MDC will be hosting the first Immunology & Inflammation Conference – or I & I Conference – in Berlin. We spoke with the two organizers, Professors Michela Di Virgilio and Klaus Rajewsky, about the conference’s aims and its program.

Face

Institute & Campus February 11, 2019

Video Portraits: Inspiring Women In Translational Medicine

For the “International Day of Girls and Women in Science” on 11 February 2019, the Berlin Institute of Health (BIH) presents ten video portraits of inspirational women scientists. Among them are four videos about scientists working at the MDC.

Institute & Campus January 31, 2019

“Haressment doesn’t happen in a vacuum”

In late January, the Anti-Harassment Task Force started its work at the MDC. More than 50 employees from all areas and across all hierarchies will develop guidelines for respectful interaction. To mark the launch of the task force, we spoke with the project facilitator, Professor Sabine Oertelt-Prigione.

Science January 31, 2019

🎧 The Future of Science is Open: new podcast

The brand new MDC-made ORION Open Science podcast explores the issues behind the Open Science movement through interviews and conversations. The first full episode on ‘Open Science and postgraduate careers’ launches January 31st.

Science January 15, 2019

▶ Video: Would you want to live forever?

Live forever thanks to CRISPR? This summer, the artist Emilia Tikka was a guest at the MDC. Her work focused on the question: What if CRISPR-Cas9 could make us immortal? The exhibition and a mini symposium are now documented on video.

Jutta Kramm

Jutta Kramm

jutta.kramm@mdc-berlin.de

Press Release

3/2019 January 31

Private donations for Alzheimer’s research

2/2019 January 21

MDC’s statement regarding the Spiegel Online article

1/2019 January 15

Europe looks to cells for a healthier future

32/2018 December 21

Tracking development cell by cell is ‘Breakthrough of the Year’ – Berlin-based MDC is a hot spot for such research

31/2018 December 12

How dietary fiber and gut bacteria protect the cardiovascular system

February 18, 2019

#Muskelschwund: Wie unsere Forscher*innen mit #Gentherapie und #Stammzellen dagegen kämpfen im @focuswissen https://t.co/3YMGyAxkzt
February 18, 2019

RT @JosefineDunst: Compelling data by Klaus Rajewsky‘s lab @MDC_Berlin support instructive role of BCR signaling in B1 cell development in…
February 17, 2019

RT @DilansuGneykaya: Check out this very cool study from our lab in @MDC_Berlin, suggesting novel #microglia signature genes! https://t.co/…
February 17, 2019

RT @mmw_lmw: #Lineage_Plasticity in #B_Cells | Mature B2 cells differentiate into a B1 cell upon acquisition of a typical B1 self-reactive…

Events

HIV-infected H9 T cell

Image · Antibodies and Complement Conference Header

Career Day MDC 2016

Carolin Barth: PhD Defence

Neuroscience Seminar Series

Neuroscience Department PhD/Postdoc Seminar Series

Stefan Donat: PhD Defence

Ina-Maria Rudolph: PhD Defence

BIH Course on Stem Cells: Training on Handling and Maintenance of Human Pluripotent Stem Cells

Familie Brasch

Philipp Wahle: PhD Defence

Bin Yue: PhD defence

Media Coverage

Focus / February 18, 2019

Die Einzigartigkeit der Hoffnung

Science Daily / February 15, 2019

On the origin of B1 cells

Nature / February 11, 2019

Europe’s next €1-billion science projects: six teams make it to final round

ZDF Morgenmagazin / January 29, 2019

Nationale Dekade gegen Krebs

Publications

The choice of embedding media affects image quality, tissue R(2)*, and susceptibility behaviors in post‐mortem brain MR microscopy at 7.0T

Synergistic activity of BET inhibitor MK-8628 and PLK inhibitor Volasertib in preclinical models of medulloblastoma

Sex differences in autoimmune disorders of the central nervous system

Semin Immunopathol

Collagen I-based scaffolds negatively impact fracture healing in a mouse-osteotomy-model although used routinely in research and clinical application

Diagnosis of obesity and use of obesity biomarkers in science and clinical medicine

February 15, 2019

BCR-dependent lineage plasticity in mature B cells

February 14, 2019

Comprehensive gene expression meta-analysis identifies signature genes that distinguish microglia from peripheral monocytes/macrophages in health and glioma

Acta Neuropathol Commun

February 13, 2019

The histone demethylase PHF8 facilitates alternative splicing of the histocompatibility antigen HLA-G

Videos