Press Releases Search Search Category Topic Search Sort by RelevanceFrom A-ZAuthored onDate/Time RangeRelease date Order AscDesc Institute & Campus (1) Press release (85) (-) Science (6) Animal Research (8) Art (1) Artificial Intelligence (4) Basic Research (2) BIH (2) BIMSB (3) Biochemistry & Proteomics (3) Campus (1) Campus Buch (1) (-) Cancer (5) Cardiovascular Research (7) Charité (3) Clinical Research (1) Computational Biology (2) CRISPR/Cas9 (4) Data science (1) Developmental Biology (3) Disease-related Research (5) DZHK (3) ECRC (1) (-) ERC (1) EU-Life (1) FMP (1) Gene Expression Regulation & RNA Biology (2) Genetics & Genomics (7) High-throughput technologies (1) History (1) Imaging (3) Immunology (3) Immunotherapy (1) LifeTime (4) MDC-Forschung (1) Metabolism (1) NAKO (1) Neuroscience (3) OpenScience (3) Organoids (4) Personalia (3) Research Highlights (10) Responsible Research (1) Signal Transduction (1) Single-cell analysis (10) Stem Cell Biology (7) Structural Biology & Biophysics (1) Systems Biology (4) Teachers & Pupils (1) Technology Platforms (1) Technology Transfer (1) Women in Science (1) Work and Family (1) 6 Results: Active Filter: ScienceCancerERC Sort: Result score Newest to oldest Oldest to newest Press Release No. 42 September 03, 2019 Berlin 📺 Research for a long life Learning from naked mole-rats is key to Jane Reznick’s research into new therapies for heart disease and strokes. She has now been awarded an ERC Starting Grant, which will help her to start her own group and fund her work to the tune of €1.55 million over five years. Press Release No. 20 May 13, 2019 Berlin Why Hodgkin’s lymphoma cells grow uncontrollably Although classical Hodgkin’s lymphoma is generally easily treatable today, many aspects of the disease still remain a mystery. A team at the MDC led by Professor Claus Scheidereit has now identified an important signaling molecule in the biology of this lymphoma: LTA. Press Release No. 18 May 03, 2019 Berlin First “wave” of the German National Cohort is completed In late April, the Berlin-North study center at the MDC welcomed its 10,000th subject in the GNC health study. This completes the first round of baseline examinations. Press Release No. 34 December 20, 2017 Berlin The dark side of treating cancer with drugs What are the consequences if a cellular aging-like program is acutely activated in tumor cells? And what role does the stem cell program play in it? Press Release No. 5 January 25, 2016 Berlin Hacking the programs of cancer stem cells All of the cells in a tumor are the offspring of a single, aberrant cell, but they are not all alike. Only a few retain the capacity of the original cell to create an entire tumor. Such cancer stem cells can migrate to other tissues and become fatal metastases. To fully cure a patient’s cancer, it is crucial to find and eliminate all of these cells because any that escape can regenerate the tumor and trigger its spread through the body. Press Release No. 27 November 04, 2015 Berlin Uptake mechanisms of cytostatics discovered How does a cytostatic like cisplatin or carboplatin actually get into the cell? Scientists at the MaxDelbrück Center for Molecular Medicine in the Helmholtz Association (MDC) and the Leibniz-Institut für Molekulare Pharmakologie (FMP) in Berlin, in cooperation with a Dutch group, have now succeeded in showing that the volume-regulated anion channel VRAC is 50 % responsible for active substance uptake. If one of the VRAC subunits LRRC8A or LRRC8D is down-regulated, cells take up considerably less of the anti-cancer drug. In addition to this finding, programmed cell death or apoptosis is also significantly disturbed when LRRC8A is missing. The researchers have thus identified a potential cause for therapy resistance.