Press Releases Search Search Category Topic Search Sort by RelevanceFrom A-ZAuthored onDate/Time RangeRelease date Order AscDesc Press release (3) Science (1) Animal Research (27) Art (4) Basic Research (4) BIH (10) BIMSB (13) Campus (1) Campus Buch (4) Campus Life (4) Cancer (19) Cardiovascular Research (25) Cell Biology (14) Charité (12) Clinical Research (5) Clinical Studies (4) Communication (1) Computational Biology (4) CRISPR/Cas9 (6) Developmental Biology (5) Disease-related Research (30) DZHK (5) ECRC (8) ERC (9) EU-Life (2) (-) FMP (3) Gene Expression Regulation & RNA Biology (6) Genetics & Genomics (22) Helmholtz (1) History (5) Imaging (6) Immunology (11) Institute (5) Labor trifft Lehrer (1) LifeTime (4) Metabolism (5) Neuroscience (23) OpenScience (1) Personalia (21) Physiology (2) Prizes & Awards (10) Research Highlight (16) science policy (1) Signal Transduction (2) Single-cell analysis (8) Stem Cell Biology (10) Structural Biology & Biophysics (4) Support for Scientists (2) Systems Biology (16) Teachers & Pupils (2) Technology Platforms (1) Technology Transfer (2) Translation (2) Women in Science (1) Work and Family (1) 3 Results: Active Filter: FMP Sort: Result score Newest to oldest Oldest to newest Press Release No. 2 February 06, 2018 Berlin How a Mutated Gene Triggers Hypertension Too much aldosterone causes hypertension. One cause is a mutation in the CLCN2 gene, which contains the blueprint for an ion channel of the adrenal cortex. Press Release No. 29 July 08, 2016 Berlin A “time switch” in the brain improves sense of smell When the brain processes olfactory stimuli, it differentiates between similar smells using subtly modulated signals. Brain examinations and behavioral studies in mice have now shown that neurons with inhibiting characteristics play a key role in this process. Press Release No. 27 November 04, 2015 Berlin Uptake mechanisms of cytostatics discovered How does a cytostatic like cisplatin or carboplatin actually get into the cell? Scientists at the MaxDelbrück Center for Molecular Medicine in the Helmholtz Association (MDC) and the Leibniz-Institut für Molekulare Pharmakologie (FMP) in Berlin, in cooperation with a Dutch group, have now succeeded in showing that the volume-regulated anion channel VRAC is 50 % responsible for active substance uptake. If one of the VRAC subunits LRRC8A or LRRC8D is down-regulated, cells take up considerably less of the anti-cancer drug. In addition to this finding, programmed cell death or apoptosis is also significantly disturbed when LRRC8A is missing. The researchers have thus identified a potential cause for therapy resistance.