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Angiotensin receptor type 1 mRNA in human right ventricular endomyocardial biopsies: downregulation in heart failure

Authors

  • V. Regitz-Zagrosek
  • J. Fielitz
  • R. Dreysse
  • A.G. Hildebrandt
  • E. Fleck

Journal

  • Cardiovascular Research

Citation

  • Cardiovasc Res 35 (1): 99-105

Abstract

  • Atrial angiotensin II receptors type 1 (AT1) are downregulated in end-stage human heart failure at mRNA and protein level. The present study investigated whether AT1 ventricular mRNA content was reduced in myocardial biopsies from heart failure patients.


DOI

doi:10.1016/S0008-6363(97)00089-8