- N. Royla
- S. Kempa
- Molecular & Cellular Oncology
- Mol Cell Oncol 4 (4): e1338209
Our recent study shows that the translation of MYC mRNA (mRNA) is controlled by its 3' untranslated region (UTR) in a process that depends on the availability of glutamine and levels of cellular nucleotides. Metabolic feedback protects cells from a lethal glutamine addiction and may compromise metabolic targeting of glutamine metabolism.