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ATACing single cells with phages

Authors

  • P. Maschmeyer
  • S. Haas

Journal

  • Molecular Cell

Citation

  • Mol Cell 82 (2): 234-236

Abstract

  • Fiskin et al. (2021) developed a "multi-omics" approach that integrates phage-displayed single-domain antibodies ("nanobodies") with the assay for transposase-accessible chromatin (PHAGE-ATAC) to simultaneously determine protein expression, chromatin accessibility, and mitochondrial DNA mutations (for clonal tracing) in single cells.


DOI

doi:10.1016/j.molcel.2021.12.028