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Chloride channel 2 gene (Clc2) maps to chromosome 16 of the mouse, extending a region of conserved synteny with human chromosome 3q

Authors

  • A. Lengeling
  • M. Gronemeier
  • M. Ronsiek
  • A. Thiemann
  • T.J. Jentsch
  • H. Jockusch

Journal

  • Genetical Research

Citation

  • Genet Res 66 (2): 175-178

Abstract

  • The Clc2 gene of the mouse codes for the ubiquitously expressed chloride channel ClC-2, a member of a family of at least seven voltage gated chloride channels, some of which are implicated in hereditary diseases. Using a mouse interspecies back-cross panel, we have mapped Clc2 to Chr 16, proximal to the somatostatin gene Smst, extending a region of documented conserved synteny to human Chr 3q.


DOI

doi:10.1017/S0016672300034522