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The dangers of transcription

Authors

  • S. Mathas
  • T. Misteli

Journal

  • Cell

Citation

  • Cell 139 (6): 1047-1049

Abstract

  • Transcription is obviously essential, but even a good thing can be dangerous at times. In this issue, Lin et al. (2009) provide evidence that binding of the transcription machinery may predispose genome regions to breakage and translocations that may lead to cancer.


DOI

doi:10.1016/j.cell.2009.11.037