folder

Die Molekuele der Metastasierung [the molecules of metastasis]

Authors

  • W. Kemmner
  • P.M. Schlag

Journal

  • Chirurgische Praxis

Citation

  • 61: 203-212

Abstract

  • Summary: Metastasis is a complex multistep process which can be crudely broken down into 4 steps: growth and vascularization of the primary tumor, loss of tissue integrity and invasion of tumor cells into the vessel system, dissemination and extravasation into the target organ, and the formation of macrometastases. Here, we will discuss which are the crucial molecules of each of these steps and give a brief introduction into novel concepts of metastasis.