folder

Drosophila development: RNA interference ab ovo

Authors

  • M. Chekulaeva
  • A. Ephrussi

Journal

  • Current Biology

Citation

  • Curr Biol 14 (11): R428-R430

Abstract

  • A novel protein required for RNA interference in Drosophila, Armitage, was identified in a screen for genes involved in embryonic axis formation. In armitage mutants, oocyte polarity and the regulation of oskar mRNA translation are impaired, suggesting that RNA silencing regulates the first steps of Drosophila development.


DOI

doi:10.1016/j.cub.2004.05.036