Erfassung selbst berichteter kardiovaskulärer und metabolischer Erkrankungen in der NAKO Gesundheitsstudie: Methoden und erste Ergebnisse [Assessment of self-reported cardiovascular and metabolic diseases in the German National Cohort (GNC, NAKO Gesundhe


  • L. Jaeschke
  • A. Steinbrecher
  • K.H. Greiser
  • M. Dörr
  • T. Buck
  • J. Linseisen
  • C. Meisinger
  • W. Ahrens
  • H. Becher
  • K. Berger
  • B. Braun
  • H. Brenner
  • S. Castell
  • B. Fischer
  • C.W. Franzke
  • S. Gastell
  • K. Günther
  • W. Hoffmann
  • B. Holleczek
  • A. Jagodzinski
  • R. Kaaks
  • A. Kluttig
  • G. Krause
  • L. Krist
  • O. Kuß
  • A.T. Lehnich
  • M. Leitzmann
  • W. Lieb
  • M. Löffler
  • K.B. Michels
  • R. Mikolajczyk
  • A. Peters
  • T. Schikowski
  • S. Schipf
  • B. Schmidt
  • M. Schulze
  • H. Völzke
  • S.N. Willich
  • T. Pischon


  • Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz


  • Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 63 (4): 439-451


  • BACKGROUND: Data on self-reported cardiovascular and metabolic diseases are available for the first 100,000 participants of the population-based German National Cohort (GNC, NAKO Gesundheitsstudie). OBJECTIVES: To describe assessment methods and the frequency of self-reported cardiovascular and metabolic diseases in the German National Cohort. MATERIALS AND METHODS: Using a computer-based, standardized personal interview, 101,806 participants (20-75 years, 46% men) from 18 nationwide study centres were asked to use a predefined list to report medical conditions ever diagnosed by a physician, including cardiovascular or metabolic diseases. For the latter, we calculated sex-stratified relative frequencies and compared these with reference data. RESULTS: With regard to cardiovascular diseases, 3.5% of men and 0.8% of women reported to have ever been diagnosed with a myocardial infarction, 4.8% and 1.5% with angina pectoris, 3.5% and 2.5% with heart failure, 10.1% and 10.4% with cardiac arrhythmia, 2.7% and 1.8% with claudicatio intermittens, and 34.6% and 27.0% with arterial hypertension. The frequencies of self-reported diagnosed metabolic diseases were 8.1% and 5.8% for diabetes mellitus, 28.6% and 24.5% for hyperlipidaemia, 7.9% and 2.4% for gout, and 10.1% and 34.3% for thyroid diseases. Observed disease frequencies were lower than reference data for Germany. CONCLUSIONS: In the German National Cohort, self-reported cardiovascular and metabolic diseases diagnosed by a physician are assessed from all participants, therefore representing a data source for future cardio-metabolic research in this cohort.