- Giulia Caglio
- E. Torlai Triglia
- A. Pombo
- Cell Stem Cell
- Cell Stem Cell 20 (5): 573-575
Enhancers exist in different epigenetic states: active, primed, or poised. However, it is not yet understood how the different enhancer states influence gene activation. In this issue of Cell Stem Cell, Cruz-Molina et al. (2017) unravel how poised enhancers activate anterior neural genes and the role of Polycomb proteins in enhancer-promoter contacts.