- E. Cano
- V. Gebala
- H. Gerhardt
- Cell Stem Cell
- Cell Stem Cell 20 (3): 296-297
For almost a decade, mesenchymal stem cells (MSCs) were believed to reside as perivascular cells in vivo. In this issue of Cell Stem Cell, Guimaraes-Camboa et al. (2017) challenge this idea and use lineage tracing to demonstrate that perivascular cells do not behave as tissue-specific progenitors in various organs, despite showing MSC potential in vitro.