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Plasma fetuin-a levels and the risk of myocardial infarction and ischemic stroke

Authors

  • C. Weikert
  • N. Stefan
  • M.B. Schulze
  • T. Pischon
  • K. Berger
  • H.G. Joost
  • H.U. Haering
  • H. Boeing
  • A. Fritsche

Journal

  • Circulation

Citation

  • Circulation 118 (24): 2555-2562

Abstract

  • Fetuin-A, a protein almost exclusively secreted by the liver, induces insulin resistance and subclinical inflammation in rodents. Circulating fetuin-A levels are elevated in humans with metabolic syndrome and insulin resistance, conditions that are associated with increased risk of cardiovascular disease.


DOI

doi:10.1161/CIRCULATIONAHA.108.814418