VGLUT2 functions as a differential marker for hippocampal output neurons
Authors
- C. Wozny
- P. Beed
- N. Nitzan
- Y. Pössnecker
- B.R. Rost
- D. Schmitz
Journal
- Frontiers in Cellular Neuroscience
Citation
- Front Cell Neurosci 12: 337
Abstract
The subiculum is the gatekeeper between the hippocampus and cortical areas. Yet, the lack of a pyramidal cell-specific marker gene has made the analysis of the subicular area very difficult. Here we report that the vesicular-glutamate transporter 2 (VGLUT2) functions as a specific marker gene for subicular burst-firing neurons, and demonstrate that VGLUT2-Cre mice allow for Channelrhodopsin-2 (ChR2)-assisted connectivity analysis.