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A woman with postoperative hyponatremia related to desmopressin acetate

Authors

  • A. Schreiber
  • S. Kubitza
  • F.C. Luft

Journal

  • American Journal of Kidney Diseases

Citation

  • Am J Kidney Dis 44 (1): E3-E6

Abstract

  • A patient was referred to the intensive care unit with sudden delirium and a serum sodium level of 111 mEq/L (mmol/L). A computerized tomographic scan revealed marked cerebral edema. Laboratory values were highly consistent with the action of the antidiuretic hormone. She had received desmopressin acetate (DDAVP) for 4 days preoperatively and postoperatively for putative van Willebrand's disease. Hyponatremia as a sequel to DDAVP treatment is an unusual complication and the medication is generally safe. However, our patient nevertheless teaches that vigilance equals avoidance.


DOI

doi:10.1053/j.ajkd.2004.04.017