Scientific Publications

Reprogramming of B lymphoid cells in human lymphoma pathogenesis

M. Janz
B. Doerken
S. Mathas

Classical Hodgkin lymphoma is characterized by high constitutive expression of activating transcription factor 3 (ATF3) which promotes viability of Hodgkin/Reed-Sternberg cells

M. Janz
M. Hummel
M. Truss
B. Wollert-Wulf
S. Mathas
K. Joehrens
C. Hagemeier
K. Bommert
H. Stein
B. Doerken
R.C. Bargou

Loss of the tissue-specific proapoptotic BH3-only protein Nbk/Bik is a unifying feature of renal cell carcinoma

I. Sturm
C. Stephan
B. Gillissen
R. Siebert
M. Janz
S. Radetzki
K. Jung
S. Loening
B. Doerken
P.T. Daniel

February, 2006 / Nat Immunol

Intrinsic inhibition of transcription factor E2A by HLH proteins ABF-1 and Id2 mediates reprogramming of neoplastic B cells in Hodgkin lymphoma

S. Mathas
M. Janz
F. Hummel
M. Hummel
B. Wollert-Wulf
S. Lusatis
I. Anagnostopoulos
A. Lietz
M. Sigvardsson
F. Jundt
K. Joehrens
K. Bommert
H. Stein
B. Doerken

Regulation des Zellzyklus und therapeutische Implikationen

H.D. Royer
E. Grinstein
M. Janz

PTEN loss defines a PI3K/AKT pathway-dependent germinal center subtype of diffuse large B-cell lymphoma

M. Pfeifer
M. Grau
D. Lenze
S.S. Wenzel
A. Wolf
B. Wollert-Wulf
K. Dietze
H. Nogai
B. Storek
H. Madle
B. Dörken
M. Janz
S. Dirnhofer
P. Lenz
M. Hummel
A. Tzankov
G. Lenz

IκB-ζ controls the constitutive NF-κB target gene network and survival of ABC DLBCL

H. Nogai
S.S. Wenzel
S. Hailfinger
M. Grau
E. Kaergel
V. Seitz
B. Wollert-Wulf
M. Pfeifer
A. Wolf
M. Frick
K. Dietze
H. Madle
A. Tzankov
M. Hummel
B. Dörken
C. Scheidereit
M. Janz
P. Lenz
M. Thome
G. Lenz

Synthesis and degradation jointly determine the responsiveness of the cellular proteome

B. Schwanhäusser
J. Wolf
M. Selbach
D. Busse