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Scientific Publications

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/ Cancers

Immune response and metastasis-links between the metastasis driver MACC1 and cancer immune escape strategies

  • S. Torke
  • W. Walther
  • U. Stein
/ Science

Touch sensation requires the mechanically gated ion channel ELKIN1

  • S. Chakrabarti
  • J.D. Klich
  • M.A. Khallaf
  • A.J. Hulme
  • O. Sánchez-Carranza
  • Z.M. Baran
  • A. Rossi
  • A.T.L. Huang
  • T. Pohl
  • R. Fleischer
  • C. Fürst
  • A. Hammes
  • V. Bégay
  • H. Hörnberg
  • R.K. Finol-Urdaneta
  • K. Poole
  • M. Dottori
  • G. Lewin
/ Cancers

MACC1 regulates LGR5 to promote cancer stem cell properties in colorectal cancer

  • M. Erdem
  • K.H. Lee
  • M. Hardt
  • J.L. Regan
  • D. Kobelt
  • W. Walther
  • M. Mokrizkij
  • C. Regenbrecht
  • U. Stein
/ Endocr-Relat Cancer

Impact of the PI3Kalpha inhibitor alpelisib on everolimus resistance and somatostatin receptor expression in an orthotopic pancreatic NEC xenograft mouse model

  • A.M. Mohan
  • S. Prasad
  • F. Schmitz-Peiffer
  • C. Lange
  • M. Lukas
  • E.J. Koziolek
  • J. Albrecht
  • D. Messroghli
  • U. Stein
  • M. Ilmer
  • K. Wang
  • L. Schober
  • A. Reul
  • J. Maurer
  • J. Friemel
  • A. Weber
  • R.A. Zuellig
  • C. Hantel
  • R. Fritsch
  • M. Reincke
  • K. Pacak
  • A.B. Grossman
  • C.J. Auernhammer
  • F. Beuschlein
  • W. Brenner
  • N. Beindorff
  • S. Nölting
/ Front Oncol

GIPC1 regulates MACC1-driven metastasis

  • F. Siegel
  • H. Schmidt
  • M. Juneja
  • J. Smith
  • P. Herrmann
  • D. Kobelt
  • K. Sharma
  • I. Fichtner
  • W. Walther
  • G. Dittmar
  • R. Volkmer
  • F.G. Rathjen
  • P.M. Schlag
  • U. Stein
/ Heliyon

H4K20me3 upregulated by reactive oxygen species is associated with tumor progression and poor prognosis in patients with hepatocellular carcinoma

  • S. Phoyen
  • A. Sanpavat
  • C. Ma-on
  • U. Stein
  • N. Hirankarn
  • P. Tangkijvanich
  • D. Jindatip
  • P. Whongsiri
  • C. Boonla
/ Biomed Pharmacother

Discovery of tetrazolo-pyridazine-based small molecules as inhibitors of MACC1-driven cancer metastasis

  • S. Yan
  • P.C. Schöpe
  • J. Lewis
  • K. Putzker
  • U. Uhrig
  • E. Specker
  • J.P. von Kries
  • P. Lindemann
  • A. Omran
  • H.E. Sanchez-Ibarra
  • A. Unger
  • M.L. Zischinsky
  • B. Klebl
  • W. Walther
  • M. Nazaré
  • D. Kobelt
  • U. Stein
/ Nat Methods

Spatiotemporal, optogenetic control of gene expression in organoids

  • I. Legnini
  • L. Emmenegger
  • A. Zappulo
  • A. Rybak-Wolf
  • R. Wurmus
  • A. Oliveras Martinez
  • C. Cerda Jara
  • A. Boltengagen
  • T. Hessler
  • G. Mastrobuoni
  • S. Kempa
  • R. Zinzen
  • A. Woehler
  • N. Rajewsky
/ Cancers

Metastasis associated in colorectal cancer 1 (MACC1) mRNA expression is enhanced in sporadic vestibular schwannoma and correlates to deafness

  • M. Breun
  • K. Flock
  • J. Feldheim
  • A. Nattmann
  • C.M. Monoranu
  • P. Herrmann
  • R.I. Ernestus
  • M. Löhr
  • C. Hagemann
  • U. Stein
/ Nat Commun

Role of TMEM100 in mechanically insensitive nociceptor un-silencing

  • T.A. Nees
  • N. Wang
  • P. Adamek
  • N. Zeitzschel
  • C. Verkest
  • C. La Porta
  • I. Schaefer
  • J. Virnich
  • S. Balkaya
  • V. Prato
  • C. Morelli
  • V. Begay
  • Y.J. Lee
  • A. Tappe-Theodor
  • G.R. Lewin
  • P.A. Heppenstall
  • F.J. Taberner
  • S.G. Lechner