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Scientific Publications

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/ Acta Neuropathol Commun

Tumor associated microglia/macrophages utilize GPNMB to promote tumor growth and alter immune cell infiltration in glioma

  • F. Yalcin
  • H. Haneke
  • I.E. Efe
  • L.D. Kuhrt
  • E. Motta
  • B. Nickl
  • C. Flüh
  • M. Synowitz
  • O. Dzaye
  • M. Bader
  • H. Kettenmann
/ Mol Cancer Ther

Elimusertib has antitumor activity in preclinical patient-derived pediatric solid tumor models

  • F.F. Pusch
  • H. Dorado Garcia
  • R. Xu
  • D. Gürgen
  • Y. Bei
  • L. Brückner
  • C. Röefzaad
  • J. von Stebut
  • V. Bardinet
  • R. Chamorro Gonzalez
  • A. Eggert
  • J.H. Schulte
  • P. Hundsdörfer
  • G. Seifert
  • K. Haase
  • B.W. Schäfer
  • M. Wachtel
  • A.A. Kühl
  • M.V. Ortiz
  • A.M. Wengner
  • M. Scheer
  • A.G. Henssen
/ Cancers

Immune response and metastasis-links between the metastasis driver MACC1 and cancer immune escape strategies

  • S. Torke
  • W. Walther
  • U. Stein
/ Brain Behav Immun

Microglial sex differences in innate high anxiety and modulatory effects of minocycline

  • B. Ugursu
  • A. Sah
  • S. Sartori
  • O. Popp
  • P. Mertins
  • I.R. Dunay
  • H. Kettenmann
  • N. Singewald
  • S.A. Wolf
/ eNeuro

The IgCAM BT-IgSF (IgSF11) is essential for connexin43-mediated astrocyte-astrocyte coupling in mice

  • L. Pelz
  • L. Dossou
  • N. Kompier
  • R. Jüttner
  • G. Siemonsmeier
  • N. Meyer
  • E.D. Lowenstein
  • I. Lahmann
  • H. Kettenmann
  • C. Birchmeier
  • F.G. Rathjen
/ Cancers

MACC1 regulates LGR5 to promote cancer stem cell properties in colorectal cancer

  • M. Erdem
  • K.H. Lee
  • M. Hardt
  • J.L. Regan
  • D. Kobelt
  • W. Walther
  • M. Mokrizkij
  • C. Regenbrecht
  • U. Stein
/ Endocr-Relat Cancer

Impact of the PI3Kalpha inhibitor alpelisib on everolimus resistance and somatostatin receptor expression in an orthotopic pancreatic NEC xenograft mouse model

  • A.M. Mohan
  • S. Prasad
  • F. Schmitz-Peiffer
  • C. Lange
  • M. Lukas
  • E.J. Koziolek
  • J. Albrecht
  • D. Messroghli
  • U. Stein
  • M. Ilmer
  • K. Wang
  • L. Schober
  • A. Reul
  • J. Maurer
  • J. Friemel
  • A. Weber
  • R.A. Zuellig
  • C. Hantel
  • R. Fritsch
  • M. Reincke
  • K. Pacak
  • A.B. Grossman
  • C.J. Auernhammer
  • F. Beuschlein
  • W. Brenner
  • N. Beindorff
  • S. Nölting
/ Front Oncol

GIPC1 regulates MACC1-driven metastasis

  • F. Siegel
  • H. Schmidt
  • M. Juneja
  • J. Smith
  • P. Herrmann
  • D. Kobelt
  • K. Sharma
  • I. Fichtner
  • W. Walther
  • G. Dittmar
  • R. Volkmer
  • F.G. Rathjen
  • P.M. Schlag
  • U. Stein
/ Biomed Pharmacother

Discovery of tetrazolo-pyridazine-based small molecules as inhibitors of MACC1-driven cancer metastasis

  • S. Yan
  • P.C. Schöpe
  • J. Lewis
  • K. Putzker
  • U. Uhrig
  • E. Specker
  • J.P. von Kries
  • P. Lindemann
  • A. Omran
  • H.E. Sanchez-Ibarra
  • A. Unger
  • M.L. Zischinsky
  • B. Klebl
  • W. Walther
  • M. Nazaré
  • D. Kobelt
  • U. Stein
/ Dis Model Mech

Neurofibromin 1 mutations impair the function of human induced pluripotent stem cell-derived microglia

  • L.D. Kuhrt
  • E. Motta
  • N. Elmadany
  • H. Weidling
  • R. Fritsche-Guenther
  • I.E. Efe
  • O. Cobb
  • J. Chatterjee
  • L.G. Boggs
  • M. Schnauß
  • S. Diecke
  • M. Semtner
  • C. Anastasaki
  • D.H. Gutmann
  • H. Kettenmann