Scientific Publications

Immune response and metastasis-links between the metastasis driver MACC1 and cancer immune escape strategies

S. Torke
W. Walther
U. Stein

High-dose chemotherapy and autologous haematopoietic stem-cell transplantation in older, fit patients with primary diffuse large B-cell CNS lymphoma (MARTA): a single-arm, phase 2 trial

E. Schorb
L.K. Isbell
A. Kerkhoff
S. Mathas
F. Braulke
G. Egerer
A. Röth
S. Schliffke
P. Borchmann
U. Brunnberg
F. Kroschinsky
R. Möhle
A. Rank
D. Wellnitz
B. Kasenda
L. Pospiech
J. Wendler
F. Scherer
M. Deckert
E. Henkes
P. von Gottberg
D. Gmehlin
M. Backenstraß
A. Jensch
E. Burger-Martin
O. Grishina
H. Fricker
N. Malenica
A. Orbán
J. Duyster
G. Ihorst
J. Finke
G. Illerhaus

MACC1 regulates LGR5 to promote cancer stem cell properties in colorectal cancer

M. Erdem
K.H. Lee
M. Hardt
J.L. Regan
D. Kobelt
W. Walther
M. Mokrizkij
C. Regenbrecht
U. Stein

Impact of the PI3Kalpha inhibitor alpelisib on everolimus resistance and somatostatin receptor expression in an orthotopic pancreatic NEC xenograft mouse model

A.M. Mohan
S. Prasad
F. Schmitz-Peiffer
C. Lange
M. Lukas
E.J. Koziolek
J. Albrecht
D. Messroghli
U. Stein
M. Ilmer
K. Wang
L. Schober
A. Reul
J. Maurer
J. Friemel
A. Weber
R.A. Zuellig
C. Hantel
R. Fritsch
M. Reincke
K. Pacak
A.B. Grossman
C.J. Auernhammer
F. Beuschlein
W. Brenner
N. Beindorff
S. Nölting

GIPC1 regulates MACC1-driven metastasis

F. Siegel
H. Schmidt
M. Juneja
J. Smith
P. Herrmann
D. Kobelt
K. Sharma
I. Fichtner
W. Walther
G. Dittmar
R. Volkmer
F.G. Rathjen
P.M. Schlag
U. Stein

H4K20me3 upregulated by reactive oxygen species is associated with tumor progression and poor prognosis in patients with hepatocellular carcinoma

S. Phoyen
A. Sanpavat
C. Ma-on
U. Stein
N. Hirankarn
P. Tangkijvanich
D. Jindatip
P. Whongsiri
C. Boonla

Discovery of tetrazolo-pyridazine-based small molecules as inhibitors of MACC1-driven cancer metastasis

S. Yan
P.C. Schöpe
J. Lewis
K. Putzker
U. Uhrig
E. Specker
J.P. von Kries
P. Lindemann
A. Omran
H.E. Sanchez-Ibarra
A. Unger
M.L. Zischinsky
B. Klebl
W. Walther
M. Nazaré
D. Kobelt
U. Stein

November 07, 2023 / Nat Commun

Transcriptional reprogramming by mutated IRF4 in lymphoma

N. Schleussner
P. Cauchy
V. Franke
M. Giefing
O. Fornes
N. Vankadari
S.A. Assi
M. Costanza
M.A. Weniger
A. Akalin
I. Anagnostopoulos
T. Bukur
M.G. Casarotto
F. Damm
O. Daumke
B. Edginton-White
J.C.M. Gebhardt
M. Grau
S. Grunwald
M.L. Hansmann
S. Hartmann
L. Huber
E. Kärgel
S. Lusatis
D. Noerenberg
N. Obier
U. Pannicke
A. Fischer
A. Reisser
A. Rosenwald
K. Schwarz
S. Sundararaj
A. Weilemann
W. Winkler
W. Xu
G. Lenz
K. Rajewsky
W.W. Wasserman
P.N. Cockerill
C. Scheidereit
R. Siebert
R. Küppers
R. Grosschedl
M. Janz
C. Bonifer
S. Mathas

Metastasis associated in colorectal cancer 1 (MACC1) mRNA expression is enhanced in sporadic vestibular schwannoma and correlates to deafness

M. Breun
K. Flock
J. Feldheim
A. Nattmann
C.M. Monoranu
P. Herrmann
R.I. Ernestus
M. Löhr
C. Hagemann
U. Stein

The DNA methylation status of the TERT promoter differs between subtypes of mature B-cell lymphomas

A.G. Kouroukli
A. Fischer
H. Kretzmer
E. Chteinberg
N. Rajaram
S. Glaser
J. Kolarova
P. Bashtrykov
S. Mathas
H.G. Drexler
H. Ohno
O. Ammerpohl
A. Jeltsch
R. Siebert
S. Bens