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Scientific Publications

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/ Oncotarget

RAGE mediates S100A4-induced cell motility via MAPK/ERK and hypoxia signaling and is a prognostic biomarker for human colorectal cancer metastasis

  • M. Dahlmann
  • A. Okhrimenko
  • P. Marcinkowski
  • M. Osterland
  • P. Herrmann
  • J. Smith
  • C.W. Heizmann
  • P.M. Schlag
  • U. Stein
/ STAR Protoc

Protocol for efficient CRISPR/Cas9/AAV-mediated homologous recombination in mouse hematopoietic stem and progenitor cells

  • N.T. Tran
  • J. Trombke
  • K. Rajewsky
  • V.T. Chu
/ Trends Biochem Sci

Charting a DNA repair roadmap for immunoglobulin class switch recombination

  • T. Saha
  • D. Sundaravinayagam
  • M. Di Virgilio
/ eLife

Protection of nascent DNA at stalled replication forks is mediated by phosphorylation of RIF1 intrinsically disordered region

  • S. Balasubramanian
  • M. Andreani
  • J. Goncalves Andrade
  • T. Saha
  • D. Sundaravinayagam
  • J. Garzón
  • W. Zhang
  • O. Popp
  • S. Hiraga
  • A. Rahjouei
  • D.B. Rosen
  • P. Mertins
  • B.T. Chait
  • A.D. Donaldson
  • M. Di Virgilio
/ Nature

Cell-type specialization is encoded by specific chromatin topologies

  • W. Winick-Ng
  • A. Kukalev
  • I. Harabula
  • L. Zea-Redondo
  • D. Szabó
  • M. Meijer
  • L. Serebreni
  • Y. Zhang
  • S. Bianco
  • A.M. Chiariello
  • I. Irastorza-Azcarate
  • C.J. Thieme
  • T.M. Sparks
  • S. Carvalho
  • L. Fiorillo
  • F. Musella
  • E. Irani
  • E.T. Triglia
  • A.A. Kolodziejczyk
  • A. Abentung
  • G. Apostolova
  • E.J. Paul
  • V. Franke
  • R. Kempfer
  • A. Akalin
  • S.A. Teichmann
  • G. Dechant
  • M.A. Ungless
  • M. Nicodemi
  • L. Welch
  • G. Castelo-Branco
  • A. Pombo
/ Sci Adv

Precise CRISPR/Cas-mediated gene repair with minimal off-target and unintended on-target mutations in human hematopoietic stem cells

  • N.T. Tran
  • E. Danner
  • X. Li
  • R. Graf
  • M. Lebedin
  • K. de la Rosa
  • R. Kühn
  • K. Rajewsky
  • V.T. Chu
/ Magn Reson

Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling

  • N. Kamdem
  • Y. Roske
  • D. Kovalskyy
  • M.O. Platonov
  • O. Balinskyi
  • A. Kreuchwig
  • J. Saupe
  • L. Fang
  • A. Diehl
  • P. Schmieder
  • G. Krause
  • J. Rademann
  • U. Heinemann
  • W. Birchmeier
  • H. Oschkinat
/ Bio-protocol

Application of a spacer-nick gene-targeting approach to repair disease-causing mutations with increased safety

  • N.T. Tran
  • M. Lebedin
  • E. Danner
  • R. Kühn
  • K. Rajewsky
  • V.T. Chu
/ Nat Methods

Multiplex-GAM: genome-wide identification of chromatin contacts yields insights overlooked by Hi-C

  • R.A. Beagrie
  • C.J. Thieme
  • C. Annunziatella
  • C. Baugher
  • Y. Zhang
  • M. Schueler
  • A. Kukalev
  • R. Kempfer
  • A.M. Chiariello
  • S. Bianco
  • Y. Li
  • T. Davis
  • A. Scialdone
  • L.R. Welch
  • M. Nicodemi
  • A. Pombo
/ Trends Immunol

DNA repair and antibody diversification: the 53BP1 paradigm

  • E. Kabrani
  • T. Saha
  • M. Di Virgilio