Scientific Publications

AI-guided pipeline for protein-protein interaction drug discovery identifies an SARS-CoV-2 inhibitor

P. Trepte
C. Secker
J. Olivet
J. Blavier
S. Kostova
S.B. Maseko
I. Minia
E. Silva Ramos
P. Cassonnet
S. Golusik
M. Zenkner
S. Beetz
M.J. Liebich
N. Scharek
A. Schutz
M. Sperling
M. Lisurek
Y. Wang
K. Spirohn
T. Hao
M.A. Calderwood
D.E. Hill
M. Landthaler
S.G. Choi
J.C. Twizere
M. Vidal
E.E. Wanker

Immune response and metastasis-links between the metastasis driver MACC1 and cancer immune escape strategies

S. Torke
W. Walther
U. Stein

Microglial sex differences in innate high anxiety and modulatory effects of minocycline

B. Ugursu
A. Sah
S. Sartori
O. Popp
P. Mertins
I.R. Dunay
H. Kettenmann
N. Singewald
S.A. Wolf

Despite the odds: formation of the SARS-CoV-2 methylation complex

A. Matsuda
J. Plewka
M. Rawski
A. Mourão
W. Zajko
T. Siebenmorgen
L. Kresik
K. Lis
A.N. Jones
M. Pachota
A. Karim
K. Hartman
S. Nirwal
R. Sonani
Y. Chykunova
I. Minia
P. Mak
M. Landthaler
M. Nowotny
G. Dubin
M. Sattler
P. Suder
G.M. Popowicz
K. Pyrć
A. Czarna

March 01, 2024 / Nat Neurosci

Proteomic and transcriptomic profiling of brainstem, cerebellum and olfactory tissues in early- and late-phase COVID-19

J. Radke
J. Meinhardt
T. Aschman
R.L. Chua
V. Farztdinov
S. Lukassen
F.W. Ten
E. Friebel
N. Ishaque
J. Franz
V.H. Huhle
R. Mothes
K. Peters
C. Thomas
S. Schneeberger
E. Schumann
L. Kawelke
J. Jünger
V. Horst
S. Streit
R. von Manitius
P. Körtvélyessy
S. Vielhaber
D. Reinhold
A.E. Hauser
A. Osterloh
P. Enghard
J. Ihlow
S. Elezkurtaj
D. Horst
F. Kurth
M.A. Müller
N.C. Gassen
J. Melchert
K. Jechow
B. Timmermann
C. Fernandez-Zapata
C. Böttcher
W. Stenzel
E. Krüger
M. Landthaler
E. Wyler
V. Corman
C. Stadelmann
M. Ralser
R. Eils
F.L. Heppner
M. Mülleder
C. Conrad
H. Radbruch

Protective role of the HSP90 inhibitor, STA-9090, in lungs of SARS-CoV-2-infected Syrian golden hamsters

L.G. Teixeira Alves
M. Baumgardt
C. Langner
M. Fischer
J. Maria Adler
J. Bushe
T.C. Firsching
G. Mastrobuoni
J. Grobe
K. Hoenzke
S. Kempa
A.D. Gruber
A.C. Hocke
J. Trimpert
E. Wyler
M. Landthaler

Herpes simplex virus type 1 modifies the protein composition of extracellular vesicles to promote neurite outgrowth and neuroinfection

G. Sun
K.A. Kropp
M. Kirchner
N. Plückebaum
A. Selich
M. Serrero
A. Dhingra
J.R. Cabrera
B. Ritter
R. Bauerfeind
E. Wyler
M. Landthaler
A. Schambach
B. Sodeik
P. Mertins
A. Viejo-Borbolla

MACC1 regulates LGR5 to promote cancer stem cell properties in colorectal cancer

M. Erdem
K.H. Lee
M. Hardt
J.L. Regan
D. Kobelt
W. Walther
M. Mokrizkij
C. Regenbrecht
U. Stein

Regulation of lymphoid-myeloid lineage bias through Regnase-1/3-mediated control of Nfkbiz

T. Uehata
S. Yamada
D. Ori
A. Vandenbon
A. Giladi
A. Jelinski
Y. Murakawa
H. Watanabe
K. Takeuchi
K. Toratani
T. Mino
H. Kiryu
D.M. Standley
T. Tsujimura
T. Ikawa
G. Kondoh
M. Landthaler
H. Kawamoto
H.R. Rodewald
I. Amit
R. Yamamoto
M. Miyazaki
O. Takeuchi

Impact of the PI3Kalpha inhibitor alpelisib on everolimus resistance and somatostatin receptor expression in an orthotopic pancreatic NEC xenograft mouse model

A.M. Mohan
S. Prasad
F. Schmitz-Peiffer
C. Lange
M. Lukas
E.J. Koziolek
J. Albrecht
D. Messroghli
U. Stein
M. Ilmer
K. Wang
L. Schober
A. Reul
J. Maurer
J. Friemel
A. Weber
R.A. Zuellig
C. Hantel
R. Fritsch
M. Reincke
K. Pacak
A.B. Grossman
C.J. Auernhammer
F. Beuschlein
W. Brenner
N. Beindorff
S. Nölting