Scientific Publications

Activation of tripartite motif containing 63 expression by transcription factor EB and transcription factor binding to immunoglobulin heavy chain enhancer 3 is regulated by protein kinase D and class IIa histone deacetylases

C. Pablo Tortola
B. Fielitz
Y. Li
J. Rüdebusch
F.C. Luft
J. Fielitz

YAP and β-catenin cooperate to drive oncogenesis in basal breast cancer

H.M. Quinn
R. Vogel
O. Popp
P. Mertins
L. Lan
C. Messerschmidt
A. Landshammer
K. Lisek
S. Château-Joubert
E. Marangoni
E. Koren
Y. Fuchs
W. Birchmeier

Functional interplay of Epstein-Barr virus oncoproteins in a mouse model of B cell lymphomagenesis

T. Sommermann
T. Yasuda
J. Ronen
T. Wirtz
T. Weber
U. Sack
R. Caeser
J. Zhang
X. Li
V.T. Chu
A. Jauch
K. Unger
D.J. Hodson
A. Akalin
K. Rajewsky

Protocol for efficient CRISPR/Cas9/AAV-mediated homologous recombination in mouse hematopoietic stem and progenitor cells

N.T. Tran
J. Trombke
K. Rajewsky
V.T. Chu

June 30, 2020 / PLoS Genet

Age-of-onset information helps identify 76 genetic variants associated with allergic disease

M.A.R. Ferreira
J.M. Vonk
H. Baurecht
I. Marenholz
C. Tian
J.D. Hoffman
Q. Helmer
A. Tillander
Vi. Ullemar
Y. Lu
S. Grosche
F. Rüschendorf
R. Granell
B.M. Brumpton
L.G. Fritsche
L. Bhatta
M.E. Gabrielsen
J.B. Nielsen
W. Zhou
K. Hveem
A. Langhammer
O.L. Holmen
M. Løset
G.R. Abecasis
C.J. Willer
N.C. Emami
T.B. Cavazos
J.S. Witte
A. Szwajda
D.A. Hinds
N. Hübner
S. Weidinger
P.K. Magnusson
E. Jorgenson
R. Karlsson
L. Paternoster
D.I. Boomsma
C. Almqvist
Y.A. Lee
G.H. Koppelman

Interactome mapping provides a network of neurodegenerative disease proteins and uncovers widespread protein aggregation in affected brains

C. Haenig
N. Atias
A.K. Taylor
A. Mazza
M.H. Schaefer
J. Russ
S.P. Riechers
S. Jain
M. Coughlin
J.F. Fontaine
B.D. Freibaum
L. Brusendorf
M. Zenkner
P. Porras
M. Stroedicke
S. Schnoegl
K. Arnsburg
A. Boeddrich
L. Pigazzini
P. Heutink
J.P. Taylor
J. Kirstein
M.A. Andrade-Navarro
R. Sharan
E.E. Wanker

B-cell-specific Myd88 L252P expression causes a premalignant gammopathy resembling IgM MGUS

K. Schmidt
U. Sack
R. Graf
W. Winkler
O. Popp
P. Mertins
T. Sommermann
C. Kocks
K. Rajewsky

The epigenetic regulator Mll1 is required for Wnt-driven intestinal tumorigenesis and cancer stemness

J. Grinat
J. Heuberger
R. Vidal
N. Goveas
F. Kosel
A. Berenguer-Llergo
A. Kranz
A. Wulf-Goldenberg
D. Behrens
B. Melcher
S. Sauer
M. Vieth
E. Batlle
A. Stewart
W. Birchmeier

From pyrazolones to azaindoles: evolution of active-site SHP2 inhibitors based on scaffold hopping and bioisosteric replacement

Y. Mostinski
G.J.J.E. Heynen
M.P. López-Alberca
J. Paul
S. Miksche
S. Radetzki
D. Schaller
E. Shanina
C. Seyffarth
Y. Kolomeets
N. Ziebart
J. de Schryver
S. Oestreich
M. Neuenschwander
Y. Roske
U. Heinemann
C. Rademacher
A. Volkamer
J.P. von Kries
W. Birchmeier
M. Nazaré

Stimulation of soluble guanylyl cyclase (sGC) by riociguat attenuates heart failure and pathological cardiac remodelling

J. Rüdebusch
A. Benkner
N. Nath
L. Fleuch
L. Kaderali
K. Grube
K. Klingel
G. Eckstein
T. Meitinger
J. Fielitz
S.B. Felix